This paper proposed an assessment framework for application of knowledge management (KM) systems, α-KMS. This framework consists of 3 approaches: technology, utilization, and integrity. In addition, each approach is composed of numerous components. A corporation with real experiences on a knowledge management system is selected for practical case study. The assessment results show that: it is not easy to evaluate KM systems’ performance through financial indictors; organizations’ culture and system are key points for a successful deployment of KM system; The popular features of KM systems are related to the routine tasks; The main purpose for users to use KM systems is not to share knowledge; Even the link between financial performance and KM systems is not significant and users do not sue the KM system frequently, most users still think the KM system should be one of ‘must-have’ information system in their corporation; Outstanding staff are the enthusiastic users of KM systems.