本研究目的在探討以不同強度的運動訓練對e 抗原陽性之慢性B型肝炎患者，其對肝臟及血液指數變化的影響。實驗方法以30名e 抗原陽性之慢性B型肝炎患者為受試者，其中10 名為中強度運動訓練組（B-M 組；20.8±0.2 歲），10 名為高強度運動訓練組（B-H 組；20.6±0.2 歲），及10 名不做任何運動之對照組（控制組；20.4±0.3歲），B-M組運動強度為心跳率130－140 次/分，B-H組運動強度為心跳率160 －170 次/分，運動訓練以原地腳踏車方式進行，時間為30 分鐘，血液樣本採集於運動前（T1）、運動後5 分鐘（T2）、運動後2 小時（T3）、運動後24 小時（T4）採集共四次，以分析肝臟及血液指數之變化。實驗結果發現：丙酮酸轉胺酶（Alanine transaminase；ALT）及草醯乙酸轉胺酶（aspartatetransaminase；AST）運動前T1，B-M 組與控制組沒有顯著差異，B-H 組與控制組在T2 有顯著差異，其它則沒有差異。鹼性磷酸酶（Alkaline phosphatase；ALP）在B-H 組，T1、T2、T3、T4之比較皆有顯著差異。白血球（White blood cell；WBC）、紅血球（Red blood cell；RBC）、血紅素（Hemoglobin；Hb）、血小板（Platelet；PLT）在B-M組及B-H 組與控制組及Ｔ1 比較皆有上升的現象，且有顯著差異。 結論：B-M 組在運動前後肝臟及血液指數並無不良之影響，B-H組有部份肝指數受影響，因此對於e 抗原陽性之慢性B 型肝炎患者，適合中、低強度之運動，而高強度運動則需適當的評估自己較為妥當。

Purpose: This study was to investigate effects of different intensity exercise on hepatic and blood parameter of e antigen positive chronic hepatitis B patients. Method: Thirty subjects with e antigen positive chronic hepatitis B were recruited. Ten of them accepted moderate intensity bicycling training (B-M Group; age=20.8±0.2 yrs) and ten accepted high intensity bicycling training (B-H Group; age=20.6±0.2 yrs) with heart rate maintained at 130-140 and 160-170 beats/min respectively. Each training was set on 30 minutes. Control group had no training (CG; age=20.4±0.3 yrs). To analyze the indicators of liver function, blood samples were drawn four times; before training (T1) and 5 minutes (T2), 2 hours (T3) and 24 hours (T4) after training. Results: The parameters of ALT, AST at T2 were higher in B-H group than that CG.. ALP parameters in B-H Group at T1, T2, T3 and T4 were significant differences. WBC, RBC, Hb and PLT in both B-H and B-M groups were higher after training (T2, T3 and T4) than that before training (T1). Conclusion: Either before or after moderate intensity exercise, we found that there were no negative influences on the blood parameters of e antigen positive chronic hepatitis patients, B-M group. On the contrast, part of the blood parameters of B-H group were affected after high intensity exercise. The conclusion can be that moderate intensity exercise is more appropriate for hepatitis B patients. As to high intensity exercises, the patients can’t be too careful to evaluate their own health condition.