Digital content has become an important industry as information age, which closely connects most aspects with media communication, learning & education, leisure entertainment and information transmission of life at all. For ill match colors with letters and background of digital content will cause obstacles to visibility and legibility. Based on inference system building with fuzzy theory and neural networks, this research sets up a method with colors input by backgrounds to infer the colors from letters. Then contribute to these two parts of digital contents, which attained to a harmonious color combination of highly visibility. Utilizing this inference of neural-fuzzy model by watching different inputs of membership to the hue gamut, each hue gamut reacts to a different predicting model for itself. As it had been trained by neural networks, specific colors of background will obtained by de-fuzzy process. After these two steps of color experiments, a practical user interface of multimedia has been built on an application system. Reiterating tests to the user interface ultimately, valid inference to legibility and visibility of match colors as it used to be.