This article will initially make an introduction of the concept and nature of amicus curiae, and then analyzes the participation of the non-governmental organizations, Civil Society and individuals as amicus curiae within the WTO dispute settlement procedure. The amicus curiae briefs hitherto have been accepted by several WTO panels and the Appellate Bodies. However, many WTO members continuingly put forward the objections to this practice, and some members moved ahead to require more explicit criteria that guides the briefs offered. Therefore, this article will discuss the implications of amicus curiae briefs within the WTO dispute settlement mechanism, and try to througly look into the reports of the panel and the Appellate Body so as to find out all relevant issues of the amicus curiae. The admissibility of amicus curiae briefs within the WTO dispute settlement mechanism essentially concerns the questions of transparency and democratization of this mechanism, and these questions entail a high degree of legal significance. Moreover, this article will outline the different options for handling these questions by the WTO dispute settlement body, emphasize the complication thereof and draw a distinction between policy arguments and legal arguments. It would be less likely that actions taken by the decision making bodies of the WTO will succeed in it without a package deal at a ministerial conference. Finally, this article conceives that it would be still necessary to establish a consistent rule or to apply a uniform practice for the consideration of amicus curiae briefs in the WTO dispute settlement procedures, and however the efficiency and the procedural justice of the WTO dispute settlement mechanism should never be affected.