In modern history of China, traditional and western culture had the process of collision, conflict and harmonization. No matter traditional academy or new developing knowledge category, they must had being orientated and transformed in modern academic system of institute and base themselves on the unprecedented changed situation. Undoubtedly, the forming of discipline has their own historical factor and culture background, accomplishing their internal decrees and regulations gradually in constant adjustment and development. Literature of foreign language is considered as a discipline and era established and later than the western nature and social science in China's modern history. This text tries to discuss about the establishment and development of foreign languages department in Beijing University and Tsing-Hua University.