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題名:運動選手胰島素敏感度之特質
書刊名:大專體育學刊
作者:吳明杰陳九州 引用關係方雩 引用關係蔡櫻蘭 引用關係陳秀華羅仁駿 引用關係黃文成
作者(外文):Wu, Ming-chiehChen, Chiu-chouFang, YuTsai, Ying-lanChen, Hsiu-huaLo, Jen-chunHuang, Wen-chen
出版日期:2009
卷期:11:3
頁次:頁95-103
主題關鍵詞:運動訓練身體質量指數胰島素濃度Exercise trainingBMIInsulin level
原始連結:連回原系統網址new window
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  • 被引用次數被引用次數:期刊(1) 博士論文(0) 專書(0) 專書論文(0)
  • 排除自我引用排除自我引用:1
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  • 點閱點閱:39
醣類為運動比賽過程主要的能源,而胰島素敏感度與醣類的吸收與儲存成正比。在臨床醫學上,血糖值廣泛地被作為葡萄糖耐受度受損和第二型糖尿病的預測指標。而大部分男性運動選手皆具正常血糖濃度,其不同空腹胰島素濃度是否可作為評估胰島素敏感度的差異,目前仍未清楚。本研究目的為了解不同空腹胰島素濃度男性運動選手的胰島素阻抗性差異。空腹血糖濃度達正常值範圍內(<100mg/dl),總計31項465名運動專長選手為研究對象。所有受試者再依空腹胰島素濃度分成三組:低胰島素組(<5mU/dl, n=146)、中胰島素組(5-9.9mU/dl, n=218)和高胰島素組(>10mU/dl, n=101)。本研究結果顯示:一、高胰島素組身體質量指數和BIA體脂肪率屬於體重過重的範圍(BMI:25.4±0.4; BIA:22.5±0.7),且兩者具高度正相關(r=0.786, p<.001);二、高胰島素組的胰島素阻抗性(HOMA-IR)為3.95±0.21、中胰島素組為1.56±0.02及低胰島素組為0.77±0.02,各組均達顯著差異(p<.001);三、空腹胰島素和HOMA-IR兩者呈現顯著高度相關(r=0.994, p<.001)。本研究結論顯示身體的胰島素阻抗性隨著體脂肪增加而提高,針對運動選手的代謝適能檢測方面,採用空腹胰島素濃度為檢驗胰島素敏感度的有效的方法。
Fasting plasma glucose is widely used to predict the impaired glucose tolerance and type 2 diabetes in various populations. The difference in fasting insulin levels for evaluating metabolic status in male athletes with normal glucose have not been demonstrated completely. Therefore, we designed this study to evaluate the insulin sensitivity in various types of athletes. In this study total 465 subjects from 31-types of sport events were participated as effective samples. All the subjects with normal plasma glucose (<100mg/dl) were matched for fasting insulin level and assigned them into three groups including: Low fasting insulin level (FIL, <5mU/dl, n=146), Medium FIL (5-9.9mU/dl, n=218), and High FIL (>10mU/dl, n=101). The results of this study showed that both BMI and fat percentage in high FIL group reaches grade-1 overweight, and a significant correlation between two obesity measures (r=0.786, p<.001). A mean HOMA-IR in three groups was significantly different from each other that is 0.77, 1.56, and 3.95 respectively. This results indicates that fasting insulin level in all subjects were significantly associated with HOMA-IR (r=0.994, p<.001). From this data it was concluded that insulin resistance was directly associated with increased body fat. In addition, measurements of both fasting insulin level and obesity standard degree are useful to predict the insulin resistance in various types of male athletes.
期刊論文
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2.Weyer, C.、Pratley, R. E.、Hanson, R. L.、Tataranni, P. A.、Bogardus, C.(2000)。A high fasting plasma insulin concentration predicts type 2 diabetes independent of insulin resistance: Evidence for a pathogenic role of relative hyperinsulinemia。Diabetes,49(12),2094-2101。  new window
3.Ghiringhello, M. T., Vieira, J. G., Tachibana, T. T., Ferrer, C., Maciel, R. M., Amioka, P. H.,Hauache, O. M., de Oliveira, C. H., Khawali, C.,、Reis, A. F.(2006)。Distribution of HOMA-IR in Brazilian subjects with different body mass indexes。Arquivos Brasileiros De Endocrinologia E Metabologia,50(3),573-574。  new window
4.Meyer, R. A., Gruber, H. E., Howard, B. A., Tabor, O. B., Murakami, T., Kwiatkowski, T. C.,Wozney, J. M.,、Hanley, E. N.(1999)。Safety of recombinant human bone morphogenetic protein-2 after spinal laminectomy in the dog。Spine,24(8),747。  new window
5.Steppan, C. M.、Bailey, S. T.、Bhat, S.、Brown, E. J.、Banerjee, R. R.、Wright, C. M.、Patel, H. R.、Ahima, R. S.、Lazar, M. A.(2001)。The hormone resistin links obesity to diabetes。Nature,409(6818),307-312。  new window
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8.Burke, J. P., Williams, K., Narayan, K. M. V., Leibson, C., Haffner, S. M.,、Stern, M. P.(2003)。A population perspective on diabetes prevention: Whom should we target for preventing weight gain?。Diabetes Care,26(7),1999-2004。  new window
9.Charles, M. A., Fontbonne, A., Thibult, N., Warnet, J. M., Rosselin, G. E.,、Eschwege, E.(1991)。Risk factors for NIDDM in white population. Paris prospective study.。Diabetes,40(7),796-799。  new window
10.Del Prato, S., Leonetti, E., Simonson, D. C., Sheehan, P., Matsuda, M.,、DeFronzo, R. A.(1994)。Effect of sustained physiological hyperinsulinemia and hyperglycemia on insulin secretion and insulin sensitivity in men。Diabetologia,37,1025-1035。  new window
11.Ferrannini, E.(1998)。Insulin resistance versus insulin deficiency in non-insulin-dependent diabetes mellitus: Problems and prospects。Endocrine Revises,19(4),477-490。  new window
12.Ferrannini, E., Natali, A., Bell, P., Cavallo-Peri n, P., Lalic, N.,、Mingr one, G.(1997)。Insulin resistance and hypersecretion in obesity。Journal of Clinical Investigation,100,1166-1173。  new window
13.Haffner, S. M., Miettinen, H., Gaskill, S. P.,、Stern, M. P.(1995)。Decreased insulin secretion and increased insulin resistance are independently related to the 7-year risk of NIDDM in Mexican-Americans。Diabetes,44(12),1386-1391。  new window
14.Jago R. Wedderkopp N. Kristensen P. L. Møller N. C. Andersen L. B. Cooper A. R.、Froberg K.(2008)。Six-year change in you th physical activity and effect on fasting insulin and HOMA-IR。American Journal of Preventive Medicine,35 (6),554-560。  new window
15.Jebb, S. A.,、Elia, M.(1993)。Techniques for the measurement of body composition: A practical guide。International Journal of Obesity and Related Metabolic Disorders,17,611-621。  new window
16.Ko, G. T., Chan, J. C., Yeung, V. T., Chow, C. C., Tsang, L. W., Li, J. K., So, W. Y., Wai, H. P.,、Cockram, C. S.(1998)。Combined use of a fasting plasma glucose concentration and HbA1c or fructosamine predicts the likelihood of having diabetes in high-risk subjects。Diabetes Care,21(8),1221-1225。  new window
17.Rao, G.(2001)。Insulin resistance syndrome。American Family Physician,63,1159-1163。  new window
18.Rizzo N. S. Ruiz J. R. Oja L. Veidebaum T.、Sjöström M.(2008)。Associations between physical activity, body fat, and insulin resistance (homeostasis model assessment) in adolescents: The European youth heart study.。American Journal of Clinical Nutrition,87(3),586-592。  new window
19.Sapin, R., Le Galudec, V., Gasser, F., Pinget, M.,、Grucker, D.(2001)。Elecsys insulin assay:Free insulin determination and the absence of cross-reactivity with insulin lispro。Clinical Chemistry,47(3),602-506。  new window
20.Shaw, J. E., Zimmet, P. Z.,、Alberti, K. G.(2006)。Point: Impaired fasting glucose: The case for the new American Diabetes Association criterion。Diabetes Care,29(5),1170-1172。  new window
21.Shaw, J. E., Zimmet, P. Z., Hodge, A. M., de Courten, M., Dowse, G. K., Chitson, P.,Tuomilehto, J.,、Alberti, K. G.(2000)。Impair ed fasting glucose: How low should it go?。Diabetes Care,23(1),34-39。  new window
22.Snijder, M. B., van Dam, R. M., Visser, M.,、Seidell, J. C.(2005)。What aspects of body fat are particularly hazardous and how do we measure them?。International Journal of Epidemiology,35 (1),83-92。  new window
圖書
1.林正常(1996)。運動生理學實驗指引。台北市:師大書苑。  延伸查詢new window
其他
1.行政院衛生署(2006)。台灣地區十大死亡原因統計調查,台北市。  延伸查詢new window
 
 
 
 
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