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題名：Cleaning Small-Volume Nebulizers: The Efficacy of Different Reagents and Application Methods
書刊名：The Journal of Nursing Research
作者：戴佳惠／林念璁／彭台珠／李茹萍
作者(外文)：Tai, Chia-hua／Lin, Nien-tsung／Peng, Tai-chu／Lee, Ru-ping
出版日期：2011
卷期：19:1
頁次：頁61-67
主題關鍵詞：清洗劑；清洗方法；小劑量噴霧器；清潔效果；Cleaning reagents；Cleaning methods；Small-volume nebulizers；Cleaning efficacy
原始連結：連回原系統網址new window
相關次數：
  • 被引用次數被引用次數:期刊(2) 博士論文(0) 專書(0) 專書論文(0)
  • 排除自我引用排除自我引用:2
  • 共同引用共同引用:0
  • 點閱點閱:45
背景 : 噴霧治療對居家臥床病人是一個重要的治療，在醫學的應用上，能降低急性與慢性的呼吸道疾病症狀。然而，小劑量噴霧器的使用也可能導致菌落叢集，而增加肺炎的危險性，故小劑量噴霧器的清潔是預防肺炎的重要因素。 目的 : 本實驗性研究的主要目的，是比較兩種不同的清潔液和三種不同清潔方法，對小劑量噴霧器的清潔效果。 方法 : 兩種不同的清潔液分別是清水和無菌蒸餾水，三種不同清潔方法分別是：a.浸泡10分鐘、b.沖洗30秒、c.浸泡10分鐘後換水沖洗30秒。實驗共分為13組，其中6組為無污染組、另7組為大腸桿菌污染組，1組污染後不經過清潔當作對照，其他12組分別進行不同的清潔液與不同方法的清潔，在噴霧器清潔後分別採樣評估菌落表現。 結果 : 研究結果顯示，不同清潔液之間的清潔效力無統計上顯著差異（p = .186），但不同清潔方式則呈現顯著差異（p < .001），浸泡10分鐘後換水沖洗30秒的清潔方式，清潔效果明顯較另兩種方式佳。 結論／實務應用 : 根據研究結果，建議在清潔小劑量噴霧器的過程中，應著重在清潔方式的選擇。本研究提供使用浸泡後沖洗的方法做為清潔小劑量噴霧器之實證。
Background: Aerosol inhalation is an important treatment for immobilized patients living at home. Aerosol application of medicine can reduce symptoms of acute and chronic respiratory tract diseases. However, aerosol therapy performed using small-volume nebulizers (SVNs) may induce bacterial colonization and increase pneumonia risk. The proper cleaning of SVNs is important to prevent pneumonia. Purpose: This experimental study was designed to compare the cleaning efficacy of two different cleaning reagents and three different cleaning methods with regard to SVNs. Methods: Tap water and sterile distilled water were used as the two cleaning reagents. The three different cleaning methods included (a) soaking the nebulizer for 10 minutes, (b) rinsing the nebulizer for 30 seconds, and (c) soaking the nebulizer for 10 minutes, changing the water, and then rinsing reagent for 30 seconds. There were 13 groups in the study. Six groups were assigned into the noncontaminated and the remaining seven were contaminated with Escherichia coli. One contaminated group was assigned with noncleaning as a positive control group, and 12 groups were assigned into each of the unique cleaning reagent + cleaning method combinations. Evaluations of microbe presence were performed by taking samples from nebulizers after cleaning. Results: Results showed insignificant differences among cleaning reagent efficacies (p = .186) and significant differences among cleaning methods (p G .001). The soak-then-rinse method was found to provide significantly better results in comparison with the other two methods. Conclusions/Implications for Practice: On the basis of the results, we suggest that SVN cleaning procedures should focus on the cleansing method. Findings provide evidence to support that the soak-then-rinse method may the preferred technique to use in cleaning SVNs.
期刊論文
1.Lin, M. F.、Peng, Y. L.、Chen, M. H.、Yeh, H. W.、Huang, M. L.(2007)。A Study on bacterial contamination of small-volume nebulizers after aerosol therapy。Infection Control Journal，17(5)，287-298。  new window
2.Jakobsson, B. M.、Onnered, A. B.、Hjelte, L.、Nystrom, B.(1997)。Low bacterial contamination of nebulizers in home treatment of cystic fibrosis patients。Journal of Hospital Infection，36(3)，201-207。  new window
3.Klevens, R. M.、Edwards, J. R.、Richards, C. L. Jr, Horan, T. C.、Gaynes, R. P.、Pollock, D. A.(2007)。Estimating health care-associated infections and deaths in U.S. hospitals, 2002。Public Health Reports，122(2)，160-166。  new window
4.Le Brun, P. P.、de Boer, A. H.、Heijerman, H. G.、Frijlink, H. W.(2000)。A review of the technical aspects of drug nebulization。Pharmacy World & Science，22(3)，75-81。  new window
5.Monforte, V.、Roman, A.、Gavalda, J.、Bravo, C.、Rodriguez, V.、Ferrer, A.、Morell, F.(2005)。Contamination of the nebulization systems used in the prophylaxis with amphotericin B nebulized in lung transplantation。Transplantation Proceedings，37(9)，4056-4058。  new window
6.Reboli, A. C.、Koshinski, R.、Arias, K.、Marks-Austin, K.、Stieritz, D.、Stull, T. L.(1996)。An outbreak of Burkholderia cepacia lower respiratory tract infection associated with contaminated albuterol nebulization solution。Infection Control and Hospital Epidemiology，17(11)，741-743。  new window
7.Blau, H.、Mussaffi, H.、Mei, Z. M.、Prais, D.、Livne, M.、Czitron, B. M.、et al.(2006)。Microbial contamination of nebulizers in the home treatment of cystic fibrosis。Child : Care, Health and Development，33(4)，491-495。  new window
8.Rau, J. L.(2005)。The inhalation of drugs : Advantages and problems。Respiratory Care，50(3)，367-382。  new window
9.Rosenfeld, M.、Emerson, J.、Astley, S.(1998)。Home nebulizer use among patients with cystic fibrosis。Journal of Pediatric，132，125-131。  new window
10.Rosenfeld, M.、Joy, P.、Nguyen, C. D.、Krzewinski, J.、Burns, J. L.(2001)。Cleaning home nebulizers used by patients with cystic fibrosis : Is rinsing with tap water enough?。Journal of Hospital Infection，49(3)，229-230。  new window
11.Rosenthal, V. D.、Maki, D. G.、Salomao, R.、Moreno, C. A.、Mehta, Y.、Higuera, F.、et al.(2006)。Device-associated nosocomial infections in 55 intensive care units of 8 developing countries。Annals of Internal Medicine，145(8)，582-591。  new window
12.Cohen, H. A.、Cohen, Z.、Pomeranz, A. S.、Czitron, B.、Kahan, E.(2005)。Bacterial contamination of spacer devices used by asthmatic children。Journal of Asthma，42(3)，169-172。  new window
13.Tablan, Ofelia C.、Anderson, Larry J.、Besser, Richard、Bridges, Carolyn、Hajjeh, Rana(20040326)。Guidelines for preventing health-care-associated pneumonia, 2003: Recommendations of CDC and the healthcare infection control practices advisory committee。Morbidity & Mortality Weekly Recommendations & Reports，53(RR-3)，1-36。  new window
14.Lester, M.K.、Flume, P. A.、Gray, S. L.、Anderson, D.、Bowman, C. M.(2004)。Nebulizer use and maintenance by cystic fibrosis patients : A survey study。Respiratory Care，49(12)，1504-1508。  new window
15.Cohen, H.A.、Kahan, E.、Cohen, Z.、Sarrell, M.、Beni, S.、Grosman, Z.(2006)。Microbial colonization of nebulizers used by asthmatic children。Pediatrics International，48(5)，454-458。  new window
16.Denton, M.、Rajgopal, A.、Mooney, L.、Qureshi, A.、Kerr, K. G.、Keer, V.(2003)。Stenotrophomonas maltophilia contamination of nebulizers used to deliver aerosolized therapy to inpatients with cystic fibrosis。Journal of Hospital Infection，55(3)，180-183。  new window
17.Dima, S.、Kritsotakis, E. I.、Roumbelaki, M.、Metalidis, S.、Karabinis, A.、Maguina, N.(2007)。Device-associated nosocomial infection rates in intensive care units in Greece。Infection Control and Hospital Epidemiology，28(5)，602-605。  new window
18.Mastro, T. D.、Fields, B. S.、Breiman, R. F.、Campbell, J.、Plikaytis, B. D.、Spika, J. S.(1991)。Nosocomial legionnaires’ disease and use of medication nebulizers。Journal of Infectious Diseases，163(3)，667-671。  new window
研究報告
1.Centers for Disease Control, Department of Health, Taiwan, ROC.(2008)。Statistics of communicable disease and surveillance report 2007。Taipei, Taiwan, ROC。  new window
學位論文
1.方瑱珮(2007)。小量噴霧器不同清潔方法的效能評估(碩士論文)。長榮大學。  延伸查詢new window
圖書
1.Willey, J. M.、Sherwood, L. M.、Woolverton, C. J.(2008)。Prescott, Harley, and Klein’s microbiology。New York。  new window
 
 
 
 
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