Nasal continuous positive airway pressure (NCPAP) has been used extensively in the treatment of infants with respiratory distress syndrome (RDS). The way to fasten the device determinates the success to go through RDS. In our unit, most of the infants need to use NCPAP, but pipeline slippage occurs frequently which causes apnea bradycardia and cynosis. Besides, resetting the device will increase the work load. The current analysis: NCPAP nursing standard does not describe in detail the way to fix pipeline. With no consistent instruction on how to fix pipeline, no comfort skill on job training among colleagues and NCPAP cap fatigue, all these led to a high NCPAP pipeline slippage rate of 131%. The following 3 methods decreased slippage rate to 28% and reduced the average number of days of NCPAP usage to 5 days, firstly, modifying the NCPAP nursing standard books, secondly, carrying out comfort skill on-job-training, and thirdly, making new device to fix pipeline. These are the best benefits of this project.