The aim of this article is to explore the nursing experiences of a patient with renal cell carcinoma who underwent hemodialysis after partial nephrectomy which was attempted in the first place to preserve his renal function. The period of nursing care was from February 28th to March 30th in 2010. Data was collected under the frame of "Gordon's 11-item Functional Health Status" with physical examinations, interviews, and daily nursing care. We found that the patient had problems including high risk of infection, fluid overload, lack of knowledge of renal replacement therapy, malnutrition, and the feeling of helplessness. Through individualized nursing care plan, the physical discomfort was relieved, and the complications of hemodialysis declined. With attentive care and providing a listening ear, the knowledge of hemodialysis and self-care improved. The patient was further encouraged to participate in deciding the treatment plan. Under family's support and the sharing of experiences with other patients, the patient acquired a positive attitude toward hemodialysis and was able to face the changes in life.