本研究目的為探討補充紅景天與冬蟲夏草複方對短期高地訓練後安靜狀態時骨骼肌與大腦組織氧合作用之影響。研究方法是以14位男性田徑選手，依最大攝氧量配對分組成安慰劑組（Placebo, P）和紅景天與冬蟲夏草複方組（Rhodiola crenulata with Cordyceps sinensis, RC）。受試者進行高地訓練（～2,000公尺）前2週開始每天補充安慰劑和紅景天與冬蟲夏草複方，連續補充至2週高地訓練結束為止，共計補充4週，RC組每日補充量為2,000毫克（1,400 mg紅景天及600 mg冬蟲夏草）。高地訓練前及2週訓練後之隔天，受試者在海平面高度測量安靜狀態時骨骼肌與大腦組織總血紅素濃度、帶氧血紅素濃度、去氧血紅素濃度及氧飽和度百分比。研究結果顯示，P組大腦組織總血紅素濃度、帶氧血紅素濃度、去氧血紅素濃度在2週高地訓練後明顯低於訓練前，RC組則能正常維持大腦組織氧氣之供應。在2週高地訓練後，P與RC兩組安靜狀態骨骼肌總血紅素濃度、帶氧血紅素濃度及氧飽和度百分比明顯高於訓練前。本研究結論：本研究證實補充紅景天與冬蟲夏草複方能明顯預防高地訓練後大腦組織總血紅素濃度、帶氧血紅素與去氧血紅素濃度下降情形。

The purpose of this study was to examine the effects of Rhodiola crenulata/Crodyceps sinensis (RC) supplementation on oxygenation levels in human skeletal muscle and brain after short-term altitude training. Fourteen male long-distance track and field athletes were evenly divided into Placebo (P) and RC/CS supplemented (RC) groups based on their sea-level VO2max. The subjects received either RC (R. crenulata 1,400 mg + C. sinensis 600 mg/day) or placebo (starch) during a 4-week training program, which consisted of 2-week sea-level training and 2-week altitude training (~2,200 m). Reduced tissue oxygenation levels (total hemoglobin, oxyhemoglobin, deox-hemoglobin and oxygen saturation percentage (%) were found in both skeletal muscle and brain tissues 1 day after altitude training. Whereas RC group better maintained oxygenation status at normal level in brain tissue following altitude training compared with the placebo group. Moreover, muscle total hemoglobin, oxyhemoglobin and oxygen saturation percentage were significantly increased in both groups after 2-week altitude training, but no significant group difference was found. Our findings conclude that RC supplementation could prevent the reduced hemodynamic state of brain.