In recent years, traditional hand-controlled consoles gradually replaced by an emerging technology, it is the promoted physical activity combined with interactive technology and games products, so called Exergames. According to the recent researchs' result showed that Exergames for people with sedentary lifestyle had the effects of health promotion, and for the handicapped patients with physical and mental disorders even had the full replacement value of rehabilitation. Therefore, this study collected the recent researchs about the Exergames for health promotion. We explored the physiological change and adaptation of people with sedentary lifestyle by the Exergames, thereby to provide the posibillity for those used Exergames as a alternative reference of physical activity.