This paper employs a Foucauldian reading of Margaret Atwood’s dystopian novels, The Handmaid’s Tale and Oryx and Crake, in terms of power, knowledge, and truth. The Handmaid’s Tale explores the appropriation of power in setting up hierarchical structure, while Oryx and Crake elaborates on the fabrication of knowledge and truth. The paper explores The Handmaid’s Tale using Foucault’s theory of normalization and the panopticon gaze. Depicting a totalitarian regime which enforces strict surveillance on women’s bodies, Atwood demonstrates how power works to regulate, classify, and exploit bodies, how power prevails and creates relations, and also, how power generates subversion and resistance. The paper also examines power relations in Oryx and Crake, focusing mainly on the extreme effect of the high-tech panopticon gaze, and the establishment of knowledge and truth through normalization. I suggest Foucault’s theory contributes to a thorough understanding of Atwood’s concept of power. The present study also shows Atwood has developed writing as her survival strategy to confront the permeability of power.