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題名:高地耐力運動對人體氧化壓力的影響
書刊名:體育學報
作者:沙部.魯比 引用關係林嘉志 引用關係潘怡廷林正常 引用關係
作者(外文):Sha Pu.Lu BiLin, Chia-chihPan, Yi-tingLin, Jung-charng
出版日期:2014
卷期:47:3
頁次:頁359-376
主題關鍵詞:氧化傷害抗氧化酶葡萄糖代謝環境Oxidative damageAntioxidant enzymesGlucose metabolismEnvironment
原始連結:連回原系統網址new window
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目的:探討高地與平地之單次耐力運動,所造成氧化壓力之影響。方法:招募健康研究對象18位(男性10位及女性8位,年齡:20.3 ± 0.4歲、身高:165.9 ± 8.0公分與體重:59.5 ± 12.0公斤)。藉由隨機交叉方式在高地與平地環境進行耐力運動時,分析其安靜(Pre)、運動後立即(Post)與運動後(10 min、60 min、120 min與240 min)的血漿生化指標。各項分析所得的數據均以平均數 ± 標準誤表示。以重複量數雙因子(環境*時間)變異數分析考驗其差異程度,顯著性訂為p < .05。結果:血比容(hematocrit, Hct)、乳酸(lactate)、尿酸(uric acid)與葡萄糖(glucose)濃度,環境主要效果達顯著差異;高地顯著高於平地環境(p < .05)。高地耐力運動後血漿總蛋白、羰基蛋白(carbonyl proteins)、硫代巴比妥酸反應物(TBARS)與氮氧化物(NOx)濃度;超氧離子歧化酶(SOD)、麩胱甘肽過氧化酶(GPx)與過氧化氫酶(CAT)活性,與平地從事耐力運動相比並無顯著的差異(p > .05)。結論:急性高地(2,400 m)耐力運動可能不會造成氧化壓力,但會增加代謝壓力。
Purpose: To compare the effects of high-altitude and sea-level acute endurance exercises on oxidative stress. Methods: Eighteen healthy subjects (10 men and 8 women, age: 20.3 ± 0.4 yrs, height: 165.9 ± 8.0 cm, weight: 59.5 ± 12.0 kg) were recruited and randomly assigned to high-altitude or sea-level environment for acute endurance exercise. Blood samples were collected at resting (Pre), post-exercise (Post), post-exercise 10 min, post-exercise 60 min, post-exercise 120 min, and post-exercise 240 min for analyzing the plasma biochemical indicators. All data were denoted by the mean ± standard error. Repeated measures two-way (environment * time) analysis of variance was adopted to test the mean differences. The level of significance was set at p < .05. Results: Environmental effects on hematocrit (Hct), lactate, uric acid and glucose concentrations were significantly higher at high altitude than those at sea level (p < .05). After endurance exercise in high-altitude environment, total plasma proteins, carbonyl proteins, thiobarbituric acid reactive substance (TBARS), nitrogen oxides concentrations (NOx), superoxide dismutase activity (SOD), glutathione peroxidase activity (GPx) and catalase activity (CAT) were non-significantly different from those in sea-level environment (p >.05). Conclusion: Acute endurance exercise at high altitude (2,400 m) might not cause oxidative stress, but would increase metabolic stress.
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