Background: The principle of using restraint should uphold minimal constraints to provide maximum security. Purpose: This study was to explore the effectiveness of modified restraint glove. Methods: This quasi-experimental study design was used. Subjects were recruited from critical care unit in medical center, during May 1 to November 30, 2007. Subjects were divided by purposive sampling into an experimental group and a control group. The experimental group received Modified Restraint Glove (MRG), whereas the control group received Traditional Restraint Glove (TRG). Research tools included Restraint Diary, Family Satisfaction of Restraints, and Nurses Satisfaction of Restraint. Results: 1) MRG n=27, TRG n=26; MRG less hands sweet, edema, tight mark than TRG ( p<.05) MRG Families n=26, TRG Families n=25, The average score of the satisfaction of restraint was 3.97±.65 (MRG Families) and 3.62±.78 (TRG Families), 3) 39 Nurses (32.1±6.1 years old), The average score of the satisfaction of restraint was 3.22±.58 (MRG Nurses) and 1.98±.96 (TRG Nurses), Nursing times of check finger blood sugar and oximeter MRG is saving the nursing times than TRG ( p<.05). Conclusions: MRG not only improvement on patient's safety but also enhance the satisfaction of patients' families and nurses, and saving the nursing times. MRG is worth popularizing.