This paper examines criminal activities and case histories of offenses related to Macau’s growing casino industry, now the highest revenue generating in the world. Being returned to China in 1999, Macau now is a Special Administrative Region (SAR) with its own governing officials who operate under China’s PRC maxim of “one country, two systems”. The dramatic rapid recent growth of the casino industry in Macau offers a unique opportunity to examine issues of crime and law enforcement within the context of the People’s Republic of China’s recently acquired political and economic stewardship in this SAR. The paper documents white-collar and organized crimes that present challenges to China now that Macau has become an international marquee.