This paper illustrates the nursing experience of caring a patient with diabetic foot complicated with peripheral arterial occlusive disease. Due to repeated wounds infections and tingling sensation over affected extremity, once again debridement surgery was performed. During the period from October 3 to 29 in 2014, data was collected by observation, direct care, interview, listening, and review of medical records. After data analysis, the nurse assessed the patient with Gordon 11 Functional Health Status Assessment tool and collected subjective and objective data to establish patient who have acute pain, changes in tissue perfusion: peripheral, high risk of infection, and anxiety. During the nursing process, under family care and support, good treatment relationship was established. We educated patient and their family members about relax skills and psychological support to release patient's discomfort. Before changing dressing, we let the patient breathe by abdominal breathing for anxiety relief. By recognizing the wound infections sign, we prevented the condition of infection exacerbated. Besides, we kept the wound clean by wound care and educated the patient and family members about skills of changing dressing. Under combinational therapy of TCM far-infrared radiation therapy with acupuncture therapy for wound healing, the patient was confident in recovery and being discharged soon. We hope to share this nursing experience for future references.