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題名：Substance Use Patterns and Cognitive Function in Patients with Methamphetamine Use: A Study of 131 Cases
書刊名：Taiwanese Journal of Psychiatry
作者：鄭映芝／王亮人／陳枻志／黃名琪／林式穀／陳志根
作者(外文)：Cheng, Ying Chih／Wang, Liang-jen／Chen, Yi-chih／Huang, Ming-chyi／Lin, Shih-ku／Chen, Chih-ken
出版日期：2016
卷期：30:2
頁次：頁128-136+a8
主題關鍵詞：甲基安非他命；認知功能；愷他命；物質濫用；Methamphetamine；Cognition；Ketamine；Substance abuse
原始連結：連回原系統網址new window
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  • 被引用次數被引用次數:期刊(1) 博士論文(0) 專書(0) 專書論文(0)
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目的：物質使用模式曾被報告會影響甲基安非他命使用者的認知功能，本研究主要是要探討哪些甲基安非他命使用變量可以預測甲基安非他命濫用者的認知功能缺損。方法：本研究為一橫斷面研究，本研究記錄甲基安非他命使用者的使用變量包括首次使用甲基安非他命年齡，使用總時間，使用量及使用其他非法藥物的經驗，並且使用遺傳研究診斷問卷表, 簡短思覺失調症認知評估 (BACS) 及簡短精神症狀量表來評估個案的精神科診斷、認知功能及精神病症狀。結果：本研究共招募131 位甲基安非他命使用者，在控制年齡、性別及教育程度等因素後，較長期使用甲基安非他命以及曾經使用愷他命與較差的工作記憶 (p ＜ 0.01)、執行功能 (p ＜ 0.05) 及BACS 綜合分數 (p ＜ 0.01 與p ＜ 0.05 ) 分析有顯著的關聯性，而甲基安非他命使用的總時間與曾經使用鴉片類物質則與注意力 (p ＜ 0.05) 及處理速度 (p ＜ 0.05) 有顯著的關聯，較年輕開始使用甲基安非他命則有較差的口語記憶 (p ＜ 0.05)，甲基安非他命的使用量則與運動速度有關聯 (p ＜ 0.05)。結論：在甲基安非他命使用個案上，甲基安非他命使用的總時間與曾經使用愷他命可預測後續認知缺損。各種甲基安非他命使用變項與不同領域的認知功能相關聯的機轉值得更深入探討。
Objective: Substance use patterns are among many factors been reported to influence the result of cognitive function in patients with methamphetamine (meth) use. In this study, we intended to study what meth use parameters can predict cognitive deficits in patients with meth use. Methods: In this cross-sectional study, we recruited meth users, to collect meth use parameters-onset age, duration, dose, and experience of other illicit drugs. The psychiatric diagnoses, cognitive function, and clinical psychopathology of each patient were evaluated using the Diagnostic Interview for Genetic Study, the Brief Assessment of Cognition in Schizophrenia (BACS), and the Brief Psychiatric Rating Scale, respectively. Results: We enrolled 131 patients with meth use. After controlling for age, sex and education, we found that long duration of meth use and experience of ketamine use were significantly associated with poor performance in working memory (p ＜ 0.01), executive function (p ＜ 0.05) and composite BACS score (p ＜ 0.01 and p ＜ 0.05, respectively), duration of meth use and experience of opioid use were significantly associated with poor attention (p ＜ 0.05), and processing speed (p ＜ 0.05). We also found that earlier age of first meth use was significantly associated with poor verbal memory (p ＜ 0.05). Amount of meth consumption was also found to be significantly associated with deficit in motor speed (p ＜ 0.05). Conclusion: Duration of meth use and experience of ketamine use predicted cognitive deficits in meth users in this study. The mechanisms behind association of various meth use parameters with deficits in different domains of cognition warrant further investigation.
期刊論文
1.Volkow, N. D.、Chang, L.、Wang, G.-J.、Fowler, J. S.、Leonido-Yee, M.、Franceschi, D.、Sedler, M. J.、Gatley, S. J.、Hitzemann, R.、Ding, Y.-S.、Logan, J.、Wong, C.、Miller, E. N.(2001)。Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers。Am J Psychiatry，158(3)，377-382。  new window
2.蔣欣穎、辜彥誠、陳志根(20130600)。Dental Manifestations Leading to Diagnosis of Methamphetamine-induced Psychotic Disorder。臺灣精神醫學，27(2)，161-164+a9。new window  延伸查詢new window
3.Chou, Y. H.、Huang, W. S.、Su, T. P.、Lu, R. B.、Wan, F. J.、Fu, Y. K.(2007)。Dopamine transporters and cognitive function in methamphetamine abuser after a short abstinence: A SPECT study。Eur Neuropsychopharmacol，17，46-52。  new window
4.Hoffman, W. F.、Moore, M.、Templin, R.、McFarland, B.、Hitzemann, R. J.、Mitchell, S. H.(2006)。Neuropsychological function and delay discounting in methamphetamine-dependent individuals。Psychopharmacology，188(2)，162-170。  new window
5.Monterosso, J. R.、Aron, A. R.、Cordova, X.、Xu, J. S.、London, E. D.(2005)。Deficits in response inhibition associated with chronic methamphetamine abuse。Drug and Alcohol Dependence，79(2)，273-277。  new window
6.Simon, S. L.、Domier, C.、Carnell, J.、Brethen, P.、Rawson, R.、Ling, W.(2000)。Cognitive impairment in individuals currently using methamphetamine。The American Journal on Addictions，9(3)，222-231。  new window
7.Panenka, W. J.、Procyshyn, R. M.、Lecomte, T.、MacEwan, G. W.、Flynn, S. W.、Honer, W. G.、Barr, A. M.(2013)。Methamphetamine use: a comprehensive review of molecular, preclinical and clinical findings。Drug and Alcohol Dependence，129(3)，167-179。  new window
8.Hart, C. L.、Marvin, C. B.、Silver, R.、Smith, E. E.(2012)。Is cognitive functioning impaired in methamphetamine users? a critical review。Neuropsychopharmacology，37，586-608。  new window
9.Scott, J. C.、Woods, S. P.、Matt, G. E.(2007)。Neurocognitive effects of methamphetamine: a critical review and meta-analysis。Neuropsychol Rev，17，275-297。  new window
10.Chang, L.、Ernst, T.、Speck, O.、Patel, H.、DeSilva, M.、Leonido-Yee, M.、Miller, E. N.(2002)。Perfusion MRI and computerized cognitive test abnormalities in abstinent methamphetamine users。Psychiatry Research: Neuroimaging，114(2)，65-79。  new window
11.Johanson, C. E.、Frey, K. A.、Lundahl, L. H.(2006)。Cognitive function and nigrostriatal markers in abstinent methamphetamine abusers。Psychopharmacology，185，327-338。  new window
12.Rippeth, J. D.、Heaton, R. K.、Carey, C. L.(2004)。Methamphetamine dependence increases risk of neuropsychological impairment in HIV infected persons。J Int Neuropsychol Soc，10，1-14。  new window
13.Chen, C. K.、Lin, S. K.、Sham, P. C.(2003)。Pre-morbid characteristics and co-morbidity of methamphetamine users with and without psychosis。Psychol Med，33，1407-1414。  new window
14.Keefe, R. S.、Goldberg, T. E.、Harvey, P. D.、Gold, J. M.、Poe, M. P.、Coughenour, L.(2004)。The Brief Assessment of Cognition in Schizophrenia: reliability, sensitivity, and comparison with a standard neurocognitive battery。Schizophr Res，68，283-297。  new window
15.Keefe, R. S.、Poe, M.、Walker, T. M.、Kang, J. W.、Harvey, P. D.(2006)。The Schizophrenia Cognition Rating Scale: an interview-based assessment and its relationship to cognition, real-world functioning, and functional capacity。Am J Psychiatry，163，426-432。  new window
16.Keefe, R. S.、Harvey, P. D.、Goldberg, T. E.(2008)。Norms and standardization of the Brief Assessment of Cognition in Schizophrenia (BACS)。Schizophr Res，102，108-115。  new window
17.McKetin, R.、McLaren, J.、Lubman, D. I.、Hides, L.(2006)。The prevalence of psychotic symptoms among metham phetamine users。Addiction，101，1473-1478。  new window
18.Sawamura, J.、Morishita, S.、Ishigooka, J.(2010)。Is there a linear relationship between the Brief Psychiatric Rating Scale and the Clinical Global Impression Schizophrenia scale? a retrospective analysis。BMC Psychiatry，10。  new window
19.Sekine, Y.、Iyo, M.、Ouchi, Y.(2001)。Methamphetamine related psychiatric symptoms and reduced brain dopamine transporters studied with PET。Am J Psychiatry，158，1206-1214。  new window
20.Marshall, J. F.、Belcher, A. M.、Feinstein, E. M.、O'Dell, S. J.(2007)。Methamphetamine-induced neural and cognitive changes in rodents。Addiction，102(Suppl 1)，61-69。  new window
21.Simon, S. L.、Dacey, J.、Glynn, S.、Rawson, R.、Ling, W.(2004)。The effect of relapse on cognition in abstinent meth amphetamine abusers。J Subst Abuse Treat，27，59-66。  new window
22.Cherner, M.、Suarez, P.、Casey, C.(2010)。Methamphetamine use parameters do not predict neuropsychological impairment in currently abstinent dependent adults。Drug Alcohol Depend，106，154-163。  new window
23.Chen, C. K.、Lin, S. K.、Chen, Y. C.(2015)。Persistence of psychotic symptoms as an indicator of cognitive impairment in methamphetamine users。Drug Alcohol Depend，148，158-164。  new window
24.Driesen, N. R.、McCarthy, G.、Bhagwagar, Z.(2013)。The impact of NMDA receptor blockade on human working memory-related prefrontal function and connectivity。Neuropsychopharmacology，38，2613-2622。  new window
25.Ke, J. J.、Chen, H. I.、Jen, C. J.(2008)。Mutual enhancement of central neurotoxicity induced by ketamine followed by methamphetamine。Toxicol Appl Pharmacol，227，239-247。  new window
26.黃名琪、林式穀、陳志根(2014)。A roller coaster from methamphetamine to ketamine。Taiwanese Journal of Psychiatry，28(4)，217-231+a6。new window  new window
27.Kuczenski, R.、Everall, I. P.、Crews, L.、Adame, A.、Grant, I.、Masliah, E.(2007)。Escalating dose-multiple binge methamphetamine exposure results in degeneration of the neocortex and limbic system in the rat。Exp Neurol，207，42-51。  new window
28.Toomey, R.、Lyons, M. J.、Eisen, S. A.(2003)。A twin study of the neuropsychological consequences of stimulant abuse。Arch Gen Psychiatry，60，303-310。  new window
29.Caligiuri, M. P.、Buitenhuys, C.(2005)。Do preclinical findings of methamphetamine-induced motor abnormalities translate to an observable clinical phenotype?。Neuropsychopharmacology，30，2125-2134。  new window
30.Gould, T. J.(2010)。Addiction and cognition。Addict Sci Clin Pract，5，4-14。  new window
31.Herbeck, D. M.、Brecht, M. L.(2013)。Substance use and mental health characteristics associated with cognitive functioning among adults who use methamphetamine。J Addict Dis，32，11-25。  new window
32.陳為堅、劉絮愷、張景瑞、Lien, Ying-Ju、Chang, Yu-Hui、胡海國(1998)。Sustained attention deficit and schizotypal personality features in nonpsychotic relatives of schizophrenic patients。The American Journal of Psychiatry，155，1214-1220。  new window
33.Nurnberger, J. I. Jr.、Blehar, M. C.、Kaufmann, C. A.、York-Cooler, C.、Simpson, S. G.、Harkavy-Friedman, J.(1994)。The Diagnostic Interview for Genetic Studies: rationale, unique features, and training. NIMH Genetics Initiative。Archives of General Psychiatry，51(11)，849-859。  new window
圖書
1.American Psychiatric Association(2013)。Diagnostic and Statistical Manual of Mental Disorders (DSM-5)。American Psychiatric Association。  new window
 
 
 
 
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