Patients who undergo anesthesia via nasotracheal intubation are at risk of nasal-ala pressure sores due to improper tube care. The occurrence of nasal-ala pressure sores and scars that they leave may cause the patient to experience negative changes to their body image and can also lead to medical disputes. The incidence of nasal-ala pressure sores in the unit is as high as 46.67%; the purpose of this project was to reduce the incidence of nasal pressure sores in patients with nasotracheal intubation during the entire surgical period. Reasons for the analysis include inconsistent processing of the nasotracheal tube by nurses, friction of the nose caused by the method used to attach the pipe and the continuous observation of the pipe, lack of effective tools for attaching the nasotracheal tube, and lack of awareness by the nursing staff for the care of the nasotracheal tube. Methods used to reduce the incidence of nasal-ala pressure sores included the development of nasotracheal tube care routine, research and development of improved nasotracheal tube attachment methods, development of a nasotracheal tube fixator, and providing on-the-job education to improve pipeline care skills, along with other measures. The team worked together to reduce the incidence to 11.42% and reach the project goal. The improved nasotracheal tube attachment method and the fixed frame developed by the project can easily be adopted by other medical institutions.