Administration of medication is the most important quality indicator in clinical practice. The problems of the medication dispensation in this project are: 1) the error of medication dispensation rate 4.47%; the medication order in computer error rate is 2.8%, and the medication order in computer error rate from total medication dispensation is 63%; 2) average time consumption of the nurses in managing the error is 22.25 minutes each unit per day. From June, 1994 to August, 1994, the quality improvement team was organized to collect data, analyze the variation, define the problem and select the problem solving strategies. The purposes of this project were: 1) to reduce the error of medication dispensation rate; 2) to reduce the medication order in computer rate; 3) to save the nurse's time in managing the medication dispensation problems. The problems have been solved. The findings are as follows: 1) Medication dispensation error rate was reduced from 4.47% to 2.37%; 2) the error of the medication order in computer error rate was reduced from 2.8% to 1.12% and 63% of the order in computer error rate was reduced to 50%; 3) the average amount of nursing time saved in each unit decreased from 22.25 to 7.6 minutes each day. The purposes of this project have been accomplished, but the policy on medication order entry to the computer by unit clerks which caused the error remains a systemic problem. The suggestion to change the policy on order entry by the physician was accepted by the hospital administrator. The quality of the medication dispensation will be further investigated.