In a normal situation mucus is found throughout the respiratory tract, including lower airways, sinuses and upper airways. Normal clearance of the airway rests on mucociliary clearance and effective cough. Mucociliary clearance is effective in distal airways in which interaction between air and liquid cannot occur. An effective cough increases the gas-liquid interaction along central airways and transporting the mucus toward the mouth either to be swallowed or expectorated. Excess pulmonary secretions can cause either full airway obstruction with subsequent absorption of gas and consequent atelectasisn or partial obstruction of airway leading to a ball-valve phenomenon and contributing to air trapping and regional overdistention. Many factors oor situations can lead to abnormal accumulations of mucus. Techniques to enhance clearance of secretions include tracheobronchial suctioning, postural drainage, chest physiotherapy, pharmacotherapy, and special beds. All these airway clearance techniques have been known most traditionally as chest physical therapy or postural drainage, percussion, and vibration or bronchial hygiene therapies. The indications, recommendations, monitoring and contraindications will be discussed.