This is study of quasi-experimental post-test-only design. The purpose was to examine the effects of cognitive-behavioral startegies for pain management of intravenous injection in preschool and school-age patients. Since March to august in 1994, 38 subjects were selected in pediatric units, then divided into experimental and control groups by non-randomization. In the experimental group, researchers provided five kinds of cognitive-behavioral strategies for pain relief, such as guided imagery, tactile transference, passive distraction, modeling and play. Then researchers have had to developed three kinds of instruments to measure children's pain behavior and pain in tensity after manipulation. Results indicated that the cognitive-behavioral strategies were significantly improved in pain relief of children during the events of intravenous injection.