本研究的目的在於檢驗CAGE酗酒篩檢問卷在台灣地區的跨文化效度。研究樣本(N=198)來自一基層醫療院所門診個案的隨機抽樣。研究者加入與台灣飲酒文化相關，且在跨文化心理語言表達上與原CAGE的"Cut-down" (C1, C2)和"Annoyance" (A1)對等的三題，形成實驗性中文版CAGE (the experimental Chinese CAGE, C-CAGE); 該問卷可以用來評估五種計分方法：CAGE, C1A1GE, C1AGE, C2A1GE and C2AGE。 所有樣本在完成C-CAGE之後均接受臨床醫師的半結構性臨床面談，以獲得酗酒的診斷。和過去西方國家的報告比較，原CAGE在本研究所表現的篩檢效能位於下限值。C2AGE的 特異度和整體準確性，顯著優於原CAGE，而C2A1GE則有較好的敏感度和較大的ROC曲線下面積值。以上均顯示從心理語言性的對等考量下，原CAGE仍有進一步改進的空間。

　　　　　An easy to use screening instrument for drinking behavior or alcohol-related illness has not been established in Taiwan. The authors examined the cross-cultural validity of the CAGE questionnaire in Chinshan, Taipei County in Taiwan. Study subjects (N=198) were outpatients randomly drawn from the primary care setting in the township. Three psycholinguistic items, equivalent to "Cut-down" (C1, C2) and "Annoyance" (A1) of CAGE, thought to be culturally relevant for people in Taiwan, were added to form an exp erimental Chinese CAGE (C-CAGE). This allowed for tests of five types of scoring combination, CAGE, C1A1GE, C1AGE, C2A1GE and C2AGE. Each subject received a semi-structured clinical interview for diagnosis of alcoholism after he or she completed a C-CAGE questionnaire. The performance of CAGE in our sample was at the lowest limit among those reported in Western countries. Compared to CAGE, C2AGE was superior in robustness for specificity and overall accuracy. C2A1GE tended to be better in sensitivity and performance for the value of the area measured by receiver operating characteristics curve analysis. This indicates that CAGE has room for further improvement under the assumption of psycholinguistic equivalence.