In recent years, the trend of spinal cord injury increases due to the chaotic traffic development, the abusive use of guns, the increase of sport injuries and so on. For those victims, they may have minor injuries or severe injuries, which cause disability or paralysis that changed their whole life, or some may even lose their life. In this article, the author applied Roy's Adaptation Model in the nursing care of a 28 year old, married female with C6-7 fracture caused by a car accident, during her hospitalization from October 15, 1998 to November 9, 1998. Nursing assessment data was collected through observations, face-to-face interviews and telephone interviews. All the data was analyzed to identify the influencing behaviors and focal, contextual, and residual stimuli according to the physiological function, self-concept, role function and interdependence mode in the Roy's Adaptation Model. The nursing diagnoses for this client were; 1.High risk for infection 2.High risk for disuse syndrome 3.Sexual dysfunction 4.Powerlessness 5.Altered role performance 6.Social isolation. Nursing interventions were implemented to establish the client's confidence, increase her understanding of the injury and infection prevention, seek for social support, and develop better support system so as to deal with the impact of the injury and establish adjustment for her new future life. The author shared this nursing experience in the hope that it might be helpful for the nursing care of spinal cord injury clients.