As a pretest of studying the advertising effect of graphic design, the tests reported in this paper are aimed to manipulate the design quality of picture and text in print advertising to produce good and bad levels. In terms of manipulation method, the design quality of picture is by drawing technique, and the text is by typography and layout. Because the major difficulties in manipulation come from changing the design quality of picture, this paper tries to compare the differences in three tests and offers some suggestions for similar manipulation in the future: (1) a picture's drawing technique has more impact on manipulating design quality than the content of picture, (2) the way of drawing the line and filling the color is suitable for manipulating a picture's design quality, (3)typography and layout have more influence on a advertisement's appearance that picture does, (4) changing the space text occupies the page affects the manipulation of text design quality, and (5) changing the space of occupation affects the manipulation of text design quality more than picture. In addition, the manipulation check items for picture and text design quality have acceptable reliability, and can be implemented in future research.