【Purpose/significance】The continuous development of the internet brings the spread and evolution of thenetwork public opinion.The research on the influence factors of multiagent reflexes of network opinion has importantpractice significance to explore the formation mechanism and countermeasures of network opinion.【Method/process】Bybuilding a network public opinion response of system dynamics model, using Vensim PLE software to simulate the model.【Result/conclusion】The result shows that the public opinion events, internet users, media, network media, and governmenthave a strong interaction with the network of public opinion.The event damage degree and the sensitivity, uses emotionalintensity, the media activity and publicity of government information and other influencing factors are analyzed, providing areference for network public opinion response.