It is commonly accepted that 1976 was a turning point for Lu Xun studies, but what remains obscure is through what ways the shift eventuated. This article, by focusing on Wang Furen’s study of Lu Xun, attempts to outline the shift with the two keywords "thought" and "spirit", and highlights his contribution of integratingfactorsof intellectuals and reality into Lu Xun studies, which is inspired by the epistemological turn. This attempt becomes the origin of a more individualized and enlightenment-oriented approaches to Lu Xun. It is in this latter period that the concept of "spirit" is emphasized, because it depicts a knowledge system different from the politicized "thought". The shift of keywords, in fact, indicates a shift of epistemology.