From the perspective of the increasing demand for decision support caused by the development of national modernization,this paper demonstrates that the service object of scientific and technical intelligence should turn to decision makers. In order to be competent to serve and lead the decision-making,the key layout of the work of scientific and technical intelligence has been explored from the aspects of work content,intelligence ability,information resource reserve,tool system and organization mode,cooperation and division of labor among institutions,personnel training and introduction.These key tasks are based on external environmental factors,such as the change of world industrial pattern,the change of national role,the state of state relations,internet information technology,and the internal factors of its own institutions and human resources construction.