The governance of inter- ethnic relations has been going throughout the whole historical process of the nation- state construction in contemporary Myanmar. The value orientation of inter- ethnic relations governance adjusts in each historical period,so the path selection of governance and application is not the same,the effect of governance varies considerably. By the means of historical investigation to the governance of inter- ethnic relations in contemporary Myanmar,it is found that the governance of inter-ethnic relations in Myanmar bears some basic characteristics such as governance subject centralization,block out of governance environment,homogenization of governance orientation and unilateralization of governance process. Frequent alternation of political power,enlarged inter- ethnic differences and internationalization of inter- ethnic relations constitute severe challenges to the governance of inter- ethnic relations in contemporary Myanmar.