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題名：口腔健康相關生活品質與阿茲海默症之相關性：系統回顧
作者：明勇
作者(外文)：MING, YUNG
校院名稱：亞洲大學
系所名稱：健康產業管理學系健康管理組
指導教授：廖宏恩
嚴雅音
學位類別：博士
出版日期：2019
主題關鍵詞：失智症；阿茲海默症；口腔健康相關的生活品質(OHRQoL)；老人口腔健康評估指標(GOHAI)；口腔健康衝擊量表(OHIP)；Dementia；Alzheimer disease；OHRQoL；GOHAI；OHIP
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問題敘述: 口腔健康相關的生活品質（OHRQoL）是評估一個人對口腔健康感受的主觀衡量標準。阿茲海默症患者（Alzheimer disease, AD）因疾病的發展造成不等程度的認知功能和日常生活活動能力受損，故需要進一步探討，以釐清AD患者的口腔健康相關的生活品質是否因認知功能障礙與口腔健康狀況而產生的負面影響。
目的: 此系統回顧的目的是瞭解AD患者的口腔健康相關的生活品質(OHRQoL)情形，並探討可能影響AD患者OHRQoL的因素。
材料和方法: 本系統性回顧針對以英文發表的量性之觀察或實驗性研究，搜尋2018 年 8 月 30 日以前，PubMed、the Cochrane Library database、Medline、EBSCO、ProQuest 和 EMBASE 等資料庫，沒有日期限制。關鍵字包括AD、oral、prosthesis和OHRQoL，由2名研究者獨立進行資料檢閱。以OHRQoL為結果(outcome)，測量OHRQoL的工具包括:老人口腔健康評估指標（the Geriatric Oral Health Assessment Index, GOHAI）和口腔健康衝擊量表(Oral Health Impact Profile, OHIP)，暴露變數(type of exposure)為AD患者的認知程度和口腔健康情況。本研究遵循系統回顧和統合分析報告專案準則(the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, PRISMA)。
結果: 共有六篇符合選入條件。樣本數從30到226個不等，5篇研究使用橫斷面研究設計，1篇是非隨機對照試驗。其中三篇研究報告，與對照組相比，AD參與者的OHRQoL得分較高，但只有1項研究顯示出統計學顯著性差異。針對4篇研究中GOHAI分數的研究進行統計分析，在AD和對照組參與者的GOHAI評分中未達統計上顯著差異[標準平均差(SMD): 0.09; 95%信賴區間(CI)：-0.66至0.85]。6 篇研究在OHRQoL的影響因素相關性研究發現，認知障礙、口腔健康情況和OHRQoL之間存在不同的相關性。一篇研究發現，認知障礙與OHRQoL呈負相關。三篇研究發現口腔健康情況（包括牙周炎、牙齦出血、探測深度> 4 mm 和原有牙齒數量）會對 AD 參與者的 OHRQoL有負面的影響。三篇研究報告顯示，假牙類型和品質對AD參與者的OHRQoL有正面的影響。
結論: OHRQoL不能完全代表AD患者的實際口腔健康問題。臨床牙醫應評估患者的口腔健康狀況，最好同時使用主觀和客觀的檢查，包括口腔和假牙狀況，以確保AD患者的口腔問題能夠及早發現並及時治療。
Statement of problem. Oral health-related quality of life (OHRQoL) is a subjective measure that assesses a person’s perception of oral health. Patients with Alzheimer disease (AD) suffer from impaired cognitive function and a compromised ability to perform activities of daily living. Further exploration is needed to clarify whether OHRQoL is negatively impacted by cognitive degeneration and oral health conditions among patients with AD.
Purpose. The purpose of this systematic review was to increase understanding of OHRQoL among patients with AD and explore factors that may affect OHRQoL.
Material and methods. Searches were conducted in PubMed, the Cochrane Library database, Medline, EBSCO, ProQuest, and EMBASE until August 30, 2018, with no date restrictions. The initial search targeted quantitative observational studies published in English that included the keywords AD, oral, prosthesis, and OHRQoL. Data extraction was independently conducted by 2 reviewers. OHRQoL was investigated as the outcome. Cognitive status and oral health conditions were treated as exposures. Tools used to measure OHRQoL included the Geriatric Oral Health Assessment Index (GOHAI) and the Oral Health Impact Profile. The research adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
Results. Six studies were included. The sample sizes ranged from 30 to 226 participants, 5 studies used cross-sectional designs, and 1 was a nonrandomized controlled trial. Three studies reported higher OHRQoL scores among participants with AD than those among controls, but only 1 study showed a statistically significant difference. A statistical analysis was conducted with 4 studies that reported GOHAI scores, and no significant differences were found in GOHAI scores between participants with AD and controls (standard mean difference 0.09; 95% confidence interval: −0.66 to 0.85). All studies that explored factors affecting OHRQoL showed different associations between cognitive impairment, oral health conditions, and OHRQoL. One study showed that cognitive impairment was negatively associated with OHRQoL. Three studies found oral health conditions (including, periodontitis, gingival bleeding, probing depth >4 mm, and number of natural teeth) impaired the OHRQoL of participants with AD. Three studies reported that prosthetic type and quality positively affected OHRQoL among participants with AD.
Conclusions. OHRQoL may not fully represent actual oral health problems of patients with AD. Clinical dentists should evaluate oral problems in this population, preferably by using both subjective and objective examinations, including oral and dental condition. This will ensure oral problems among patients with AD can be detected early and timely treatment provided.
ADI. (2018). World Alzheimer Report 2016. Alzheimer’s Disease International. Retrieved from https://www.alz.co.uk/research/worldalzheimerreport2016sheet.pdf Accessed 21 Jan. 2019.
Ang, E. T., Tai, Y. K., Lo, S. Q., Seet, R., & Soong, T. W. (2010). Neurodegenerative diseases: exercising toward neurogenesis and neuroregeneration. Frontiers in Aging Neuroscience, 2, 25. doi:10.3389/fnagi.2010.00025
Atchison, K. A., & Dolan, T. A. (1990). Development-of-the-geriatric-oral-health-assessment-index. Journal of Dental Education, 54(11), 680-687.
Bakke, M., Larsen, S. L., Lautrup, C., & Karlsborg, M. (2011). Orofacial function and oral health in patients with Parkinson's disease. European Journal of Oral Sciences, 119(1), 27-32. doi:10.1111/j.1600-0722.2010.00802.x
Barbe, A. G., Bock, N., Derman, S. H., Felsch, M., Timmermann, L., & Noack, M. J. (2017). Self-assessment of oral health, dental health care and oral health-related quality of life among Parkinson's disease patients. Gerodontology, 34(1), 135-143. doi:10.1111/ger.12237
Bennadi, D., & Reddy, C. (2013). Oral health related quality of life. Journal of International Sociality of Preventive & Community Dentisstry, 3(1), 1-6. doi: 10.4103/2231-0762.115700
Benedictus, M. R., Leeuwis, A. E., Binnewijzend, M. A., Kuijer, J. P., Scheltens, P., Barkhof, F., . . . Prins, N. D. (2017). Lower cerebral blood flow is associated with faster cognitive decline in Alzheimer's disease. European Radiology, 27(3), 1169-1175. doi:10.1007/s00330-016-4450-z
Bredesen, D. E., Amos, E. C., Canick, J., Ackerley, M., Raji, C., & Fiala, M. (2016). Reversal of cognitive decline in Alzheimer’s disease. Aging, 8(6), 1250-1258. doi:10.18632/aging.100981
Buset, S. L., Walter, C., Friedmann, A., Weiger, R., Borgnakke, W. S., Zitzmann, N. U. (2016). Are periodontal diseases really silent? A systematic review of their effect on quality of life. Journal Clinical Periodontology, 43(4), 333-44. doi.org/10.1111/jcpe.12517
Buunk-Werkhoven, Y., Dijkstra-le Clercq, M., Verheggen-Udding, E., de Jong, N., & Spreen, M. (2012). Halitosis and oral health-related quality of life: a case report. International Journal of Dental Hygine, 10(1), 3-8. doi:10.1111/j.1601-5037.2011.00512.x
Boesveldt S, Bobowski N, McCrickerd K, Maître I, Sulmont-Rossé C, Forde CG. (2018). The changing role of the senses in food choice and food intake across the lifespan. Food Quality and Preference, 68, 80-9. doi.org/10.1016/j.foodqual.2018.02.004
Campos, C. H., Ribeiro, G. R., & Rodrigues Garcia, R. C. (2016). Oral health-related quality of life in mild Alzheimer: patient versus caregiver perceptions. Special Care in Dentistry, 36(5), 271-276. doi:10.1111/scd.12178
Campos, C. H., Ribeiro, G. R., & Rodrigues Garcia, R. C. M. (2017). Mastication and oral health-related quality of life in removable denture wearers with Alzheimer disease. Journal of Prosthetic Dentisty, 119(5), 764-768. doi:10.1016/j.prosdent.2017.07.010
Chen, H., Iinuma, M., Onozuka, M., & Kubo, K. Y. (2015). Chewing maintains hippocampus-dependent cognitive function. International Journal of Medical Sciences, 12(6), 502-509. doi:10.7150/ijms.11911
Chen, X., Clark, J. J., & Naorungroj, S. (2013). Oral health in nursing home residents with different cognitive statuses. Gerodontology, 30(1), 49-60. doi:10.1111/j.1741-2358.2012.00644.x
Chen H, Zhang G, Weigl P, Gu X. (2018). Immediate placement of dental implants into infected versus noninfected sites in the esthetic zone: a systematic review and meta-analysis. J Prosthet Dent, 120(5), 658-67. doi.org/10.1016/j.prosdent.2017.12.008
Cicciu, M., Matacena, G., Signorino, F., Brugaletta, A., Cicciu, A., & Bramanti, E. (2013). Relationship between oral health and its impact on the quality life of Alzheimer's disease patients: a supportive care trial. International Journal of Clinical Experimental Medicine, 6(9), 766-772. PMID: 24179569
Elsig, F., Schimmel, M., Duvernay, E., Giannelli, S. V., Graf, C. E., Carlier, S., . . . Muller, F. (2015). Tooth loss, chewing efficiency and cognitive impairment in geriatric patients. Gerodontology, 32(2), 149-156. doi:10.1111/ger.12079
El Osta, N., Tubert-Jeannin, S., Hennequin, M., Bou Abboud Naaman, N., El Osta, L., Geahchan, N. (2012). Comparison of the OHIP-14 and GOHAI as measures of oral health among elderly in Lebanon. Health and Quality Life Outcomes, 10(1), 131. doi: 10.1186/1477-7525-10-131
Faggion, Jr. C. M., (2016). Critical appraisal of evidence supporting the placement of dental implants in patients with neurodegenerative diseases. Gerodontology, 33(1), 2-10. doi:10.1111/ger.12100
Ghezzi, E. M., & Ship, J. A. (2000). Dementia and oral health. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 89(1), 2-5. doi:org/10.1016/S1079-2104(00)80003-7
Gil-Montoya, J. A., Ponce, G., Lara, I. S., Barrios, R., Llodra, J. C., & Bravo, M. (2013). Association of the oral health impact profile with malnutrition risk in Spanish elders. Archives of gerontology and geriatrics, 57(3), 398-402. doi.org/10.1016/j.archger.2013.05.002
Groupt, W. H. O. Q. O. L. (1993). Study protocol for the World Health Organization project to develop a quality of life assessment instrument (WHOQOL). Quality of Life Research,2(2), 153-9.
Harding, A., Gonder, U., Robinson, S. J., Crean, S., & Singhrao, S. K. (2017). Exploring the Association between Alzheimer's Disease, Oral Health, Microbial Endocrinology and Nutrition. Front. Aging Neurosci, 9, 398. doi:10.3389/fnagi.2017.00398
Hines, S., Wilson, J., McCrow, J., Abbey, J., & Sacre, S. (2010). Oral liquid nutritional supplements for people with dementia in residential aged care facilities: a systematic review. JBI Database of Systematic Reviews and Implementation Reports, 8(1), 1-52. doi: 10.11124/jbisrir-2010-97
Hirano, Y., Obata, T., Kashikura, K., Nonaka, H., Tachibana, A., Ikehira, H., & Onozuka, M. (2008). Effects of chewing in working memory processing. Neuroscience Letters, 436(2), 189-192. doi:10.1016/j.neulet.2008.03.033
Hatipoglu, M. G., Kabay, S. C., Guven, G. (2011). The clinical evaluation of the oral status in Alzheimer-type dementia patients. Gerodontology; 28(4), 302-6. doi.org/10.1111/j.1741-2358.2010.00401.x
Haag, D. G., Peres, K. G., Balasubramanian, M., Brennan, D.S. (2017). Oral conditions and health-related quality of life: a systematic review. Journal of Dental Reseach, 96(8), 864-74. doi: 10.1177/0022034517709737
Hsu, K. J., Lee, H. E., Wu, Y. M., Lan, S. J., Huang, S. T., & Yen, Y. Y. (2013). Masticatory factors as predictors of oral health-related quality of life among elderly people in Kaohsiung City, Taiwan. Quality of Life Research, 23(4), 1395–1405. doi:10.1007/s11136-013-0574-7
Ikebe, K., Hazeyama, T., Enoki, K., Murai, S., Okada, T., Kagawa, R., ... & Maeda, Y. (2012). Comparison of GOHAI and OHIP‐14 measures in relation to objective values of oral function in elderly Japanese. Community dentistry and oral epidemiology, 40(5), 406-414. doi.org/10.1111/j.1600-0528.2012.00683.x
Kato, T., Usami, T., Noda, Y., Hasegawa, M., Ueda, M., & Nabeshima, T. (1997). The effect of the loss of molar teeth on spatial memory and acetylcholine release from the parietal cortex in aged rats. Behavioural Brain Research, 83(1-2), 239-242. doi.org/10.1016/S0166-4328(97)86078-0
Klotz, A. L., Hassel, A. J., Schroder, J., Rammelsberg, P., & Zenthofer, A. (2017). Oral health-related quality of life and prosthetic status of nursing home residents with or without dementia. Clinical Interventions in Aging, 12, 659-665. doi:10.2147/cia.S125128
Kamer, A. R., Craig, R. G., Dasanayake, A. P., Brys, M., Glodzik-Sobanska, L., & de Leon, M. J. (2008). Inflammation and Alzheimer's disease: possible role of periodontal diseases. Alzheimer's & Dementia, 4(4), 242-250. doi:10.1016/j.jalz.2007.08.004
Lee, I. C., Shieh, T. Y., Yang, Y. H., Tsai, C. C., & Wang, K. H. (2007). Individuals' perception of oral health and its impact on the health-related quality of life. Journal of Oral Rehabilitation, 34(2), 79-87. doi:10.1111/j.1365-2842.2006.01694.x
Lee, K. H., Wu, B., & Plassman, B. L. (2013). Cognitive function and oral health-related quality of life in older adults. Journal of the America Geriatrics Society, 61(9), 1602-1607. doi:10.1111/jgs.12402
Locker, D, Slade, G. (1994). Association between clinical and subjective indicators of oral health status in an older adult population. Gerodontology, 11(2), 108-14. doi.org/10.1111/j.1741-2358.1994.tb00116.x
Locker, D., Matear, D., Stephens, M., Lawrence, H., Payne, B. (2001). Comparison of the GOHAI and OHIP-14 as measures of the oral health-related quality of life of the elderly. Community Dentistry Oral Epidemiology, 29(5), 373-81. doi.org/10.1111/j.1600-0528.2001.290507.x
Lu, H. X., Chen, X. L., Wong, M., Zhu, C., & Ye, W. (2017). Oral health impact of halitosis in Chinese adults. Int J Dent Hyg, 15(4), e85-e92. doi:10.1111/idh.12242
Marcenes, W., Kassebaum, N. J., Bernabé, E., Flaxman, A., Naghavi, M., Lopez, A., & Murray, C. J. (2013). Global burden of oral conditions in 1990–2010: a systematic analysis. J Dent Res, 92(7), 592-7. doi: 10.1177/0022034513490168
Miller, E. A., Schneider, L. S., Rosenheck, R. A. (2011). Predictors of Nursing Home Admission among Alzheimer's Disease Patients with Psychosis and/or Agitation. International Psychogeriatry, 23(1), 44-53. doi:10.1017/S1041610210000244.
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & Group, P. (2009). Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Annals of Internal Medicine, 151(4), 264-269. doi:10.1371/journal.pmed.1000097
Moola S, Munn Z, Tufanaru C, Aromataris E, Sears K, Sfetcu R, et al. (2017). Chapter 7: Systematic reviews of etiology and risk. In Aromataris E, Munn Z (Editors). Joanna Briggs Institute Reviewer’s Manual (4th ed.) Adelaide: Joanna Briggs Institute;.
Onozuka, M., Fujita, M., Watanabe, K., Hirano, Y., Niwa, M., & Nishiyama, K., et al. (2003). Age-related changes in brain regional activity during chewing: A Functional magnetic resonance imaging study. J Dent Res, 82(8), 657–660. doi:10.1177/154405910308200817
Onozuka M, Watanabe K, Fujita M, Tomida M, Ozono S. (2002). Changes in the septohippocampal cholinergic system following removal of molar teeth in the aged SAMP8 mouse. Behavioural Brain Research, 133(2), 197-204. doi: 10.1016/s0166-4328(02)00006-2.
Onozuka M, Fujita M, Watanabe K, Hirano Y, Niwa M, Nishiyama K, et al. (2003). Age-related changes in brain regional activity during chewing: a functional magnetic resonance imaging study. J Dent Res;82(8), 657-60. doi.org/10.1177/154405910308200817
Peters, M. D., Godfrey, C. M., Khalil, H., McInerney, P., Parker, D., & Soares, C. B. (2015). Guidance for conducting systematic scoping reviews. International Journal of Evidence-based Healthcare, 13(3), 141-146. doi: 10.1097/XEB.0000000000000050
Ribeiro, G. R., Costa, J. L. R, Ambrosano, G. M. B., & Garcia, R. C. M. R. (2012). Oral health of the elderly with Alzheimer's disease. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 114(3), 338-343. doi:10.1016/j.oooo.2012.03.028
Rodakowska, E., Mierzyńska, K., Bagińska, J., & Jamiołkowski, J. (2014). Quality of life measured by OHIP-14 and GOHAI in elderly people from Bialystok, north-east Poland. BMC Oral Health, 14(1). doi:10.1186/1472-6831-14-106
Slade GD, & Spencer AJ. (1994). Development and evaluation of the oral health impact profile. Community Dental Health, 11(1), 3-11. PMID:8193981
Seab, J. P., Jagust, W. J., Wong, S. T. S., Roos, M. S., Reed, B. R., & Budinger, T. F. (1988). Quantitative NMR measurements of hippocampal atrophy in Alzheimer's disease. Magnetic Resonance in Medicine, 8(2), 200-208. doi:org/10.1002/mrm.1910080210
Swaminathan, A., & Jicha, G. A. (2014). Nutrition and prevention of Alzheimer's dementia. Front Aging Neurosci, 6, 282. doi:10.3389/fnagi.2014.00282
Tada, A., & Miura, H. (2014). Systematic review of the association of mastication with food and nutrient intake in the independent elderly. Archives of gerontology and geriatrics, 59(3), 497-505. doi:10.1016/j.archger.2014.08.005
Taraghi, Z., Fanni-Saberi, L., Yazdani-Charati, J., Meskini, L. (2017). The relationship between oral health and cognitive status of the elderly. Iranian Red Crescent Medical Journal, 19, e14973.
doi: 10.5812/ircmj.14973
Teixeira, F. B., Fernandes, L. D. M. P., Noronha, P. A. T., dos Santos, M. A. R., Gomes-Leal, W., Maia, C. D. S. F., & Lima, R. R. (2014). Masticatory deficiency as a risk factor for cognitive dysfunction. International Journal of Medical Sciences, 11(2), 209-14. doi: 10.7150/ijms.6801
The University of Adelaide. (2017). New JBI grades of recommendation. In Aromataris E, Munn Z (Editors). Joanna Briggs Institute Reviewer’s Manual. 4th ed. Adelaide: Joanna Briggs Institute.
Watanabe, Y., Hirano, H., & Matsushita, K. (2015). How masticatory function and periodontal disease relate to senile dementia. Japanese Dental Science Review, 51(1), 34-40. doi:10.1016/j.jdsr.2014.09.002
Zuluaga, D. J., Montoya, J. A., Contreras, C. I., & Herrera, R. R. (2012). Association between oral health, cognitive impairment and oral health-related quality of life. Gerodontology, 29(2), e667-673. doi:10.1111/j.1741-2358.2011.00542.x

 
 
 
 
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