The purpose of this paper was to explore the risk factors of suicide died cases who drank strong acid or alkali solution. Retrospective study design was conducted and 169 subjects (ICD number 947.3 and 947.2) were collected in a medical center hospital in central Taiwan. Data collected from 1st January 1997 and 31st December 2001. Logistical regression analysis was used for EOR (estimate odds ratio). The results showed: (1) There were 17.2% suicide cases died. (2) the most suicide solution cases used were washing toilet solution and HCI (79.2%). (3) The major cause cases suicide was emotional disorder (42.0%). (4) Under controlling others variables, there were three factors related to suicide died cases, i.e. suicide causes (emotional disorder /others variables OR=9.959), treatment (invasive/ observation OR=6.491), PH value (abnormal/ normal OR=5.397). According this results, researcher recommend nurses in emergency room must pay more attention when suicide cases who is PH value abnormal, and accepted invasive treatment, should monitoring their PH value to prevent patient died.