本研究目的旨在探討兩種穴位按壓於乳癌化療病人噁心嘔吐之效果。採實驗研究設計，以中部某醫學中心門診化療室，實驗組病人接受內關穴按壓、對照組病人接受後谿穴按壓，按壓時間共15分鐘，觀察紀錄化療期間有無噁心、嘔吐，個案當日化療結束返家，隔日電訪返家24小時內之噁心嘔吐情形。研究統計結果兩組間基本屬性、癌症分期、藥物類別及血壓呼吸等控制變項均未達顯著差異，研究結果以GEE分析證實2組乳癌病人於門診化療滴注期間穴位按壓對噁心程度的緩解有明顯下降，返家後接受內關穴按壓其噁心程度緩解相較對照組效果顯著（p<.05），另按壓內關穴及後谿穴對於乳癌病人化療滴注期間有減少嘔吐次數之效果（p<.05）。針對本研究結果不論按壓內關穴或後谿穴均能緩解門診乳癌化療病人化療滴注期間之噁心嘔吐，建議此一非侵入性照護措施值得推薦於臨床照護，以提升乳癌化療病人生活品質。

This study focused on the antiemetic efficacy of compression on two acupuncture points for breast cancer patients who received chemotherapy. All patients in this study were treated in a medical center over central Taiwan and received their chemotherapy in an outpatient setting. Patients who received Neiguan and Hou-Xi compressions were divided into experimental and control groups, respectively. The duration of each acupuncture point compression was 15 minutes. The purpose of this study was to observe nausea and vomiting occurrence during and after 24 hours of chemotherapy. Comparisons of patients' clinical characteristics, cancer stages, and chemotherapy regimens between these two groups were analyzed and no significant differences were found. GEE analysis showed that acupuncture point compression could significantly decrease the occurrence of nausea and vomiting for patients in both groups. Moreover, patients who received Neiguan compression experienced less nausea than those who received Hou-Xi compression after discharge (p<.05). Our study results demonstrated that both Neiguan and Hou-Xi compressions could effectively palliate nausea and vomiting among breast cancer patients. Our study further suggests that this non-invasive procedure should be widely applied to clinical nursing care in order to improve the quality of life of breast cancer patients.