Because lung cancer ranked as the most fatal among all forms of cancer, patients suffer both tremendous physical and psychological conflicts in their terminal stage of the illness. Advance discussion about patients' self-perception were not found in the literature. The objective of this study was to investigate the stressors and coping strategies of one hospitalized patient with terminal stage lung cancer. Field study method was applied. Data were collected through nursing process recording, and then analyzed using content analysis. Results showed stressors included physical pain, dyspnea, loss of physical function, and sense of insecurity. The coping strategies included self-explanation, seeking for effective strategies, refusal, praying for extrication, and being under the constraint of fate. Nurses should realize the stressors that patients face and the coping strategies they use. Thus, more appropriate nursing care could be provided to help reduce the patients' stress produced by the disease to promote patients' quality of life.