The purpose of this case study was to explore the behavioral responses of a ligated woman who had become pregnant after assisted reproductive technology, to receiving termination in the second trimester of pregnancy. The field method was used and data were collected through nursing process recording and analyzed with content analysis. Three main areas of her behavior were inductively identified: (1) Concern about her physical changes; (2) Mothering tasks; (3) Behavioral responses and adaptation to termination. Assisted reproductive technology had given her hope, but the failure of her pregnancy made her very sad. She needed support and understanding, and to share her experience with others. The findings of this case study can provide useful information for nurses when caring for such women.