本研究目的在探討不同方式輔酪QI0的補充，對受試者於次最大運動時之攝氧量及運動後恢復期生理生化反應之影響。以中國文化大學男子甲二級籃球代表隊8名為受試對象，平均年齡20，6±1.13歲，身高184±6.48公分，體重72.3±7.97公斤。每位受試者均需從事三次80%VO2max之運動強度於原地跑步機上持續運動30分鐘，且於運動前分別接受無補充、持續補充七天、運動前補充等三種Q10補充方式，並於運動中測量其攝氧量，於運動後恢復期測量其心跳率、血壓；並以靜脈滯留針在第3、5、7、9、12、15、20、30、60分鐘，抽取肘前靜脈血，測量血乳酸值；第15、30、60分鐘抽血，分析各項血液生化值；第30、60分鐘及隔日清晨採取受試者之尿液分析各項尿液生化值。所得資料以相依樣本單因子變異數分析進行之。結果發現，不論是運動前高劑量(360mg)的輔酪Q10補充或是連續補充七天，皆可降低次最大運動時之運動中攝氧量；且運動前高劑量補充組之運動中攝氧量又低於連續補充七天組。在運動後恢復期方面，運動前高劑量之補充組於運動後恢復期30分鐘內各時段之血乳酸值及第60分鐘之尿膽原均顯著低於無補充組；而連續補充七天組則於運動後恢復期第5、7、12、15分鐘之血乳酸值顯著低於無補充組。本研究結論出，輔酶Q10可降低次最大運動時之耗氧量及加速運動後恢復期30分鐘內血乳酸之排除。

The purpose of this study was to investigate the effect of different Coenzyme Q10 supplementations on the V02max during sub-maximum exercise and biochemistry reaction during recovery. Eight A2-level male basketball players of Chinese Culture University participated as subjects (age: 20.6±1.13 yr, height: 184± 6.48 cm, weight: 72.3±7.97 kg). Each of the subjects engaged in three bouts of running on treadmill with the intensity of 80% V02max Before these three bouts of running, the subjects received different Coenzyme Q10 supplementations (non-supplementation, 7-day continuous supplementation and high-dose pre-exercise supplementation, respectively). V02 was measured during exercise. The heart rate and blood pressure were measured right after exercise. Blood samples were collected at 3, 5, 7, 9, 12, 15, 20, 30 and 60 minutes after exercise in order to determine the concentration of the blood lactate. Blood samples collected at 15, 30, 60 min after exercise were also used to determine other biochemistry indices (creatine kinase [CK] and blood urea nitrogen [BUN]). Urine samples were collected at 30, 60 minutes after exercise and the next morning (urobilinogen, proteinuria were determined). Data were analyzed by using one-way ANOVA. The results revealed that 7-day continuous supplementation and pre-exercise high-dose supplementation of Coenzyme Q10 were significantly lower V02 during exercise. The effect of pre-exercise supplementation on lowering V02 was significantly greater than 7-day continuous supplementation. The blood lactate within 30 minutes during recovery and urobilinogen at 60 minutes after exercise of the high-dose pre-exercise supplementation group were significantly lower than the non-supplementation group. The blood lactate at 5, 7, 12 and 15 minutes after exercise of the 7 -day continuous supplementation group were significantly lower than those of the non-supplementation group. It is concluded that Coenzyme Q10 can significantly improve the aerobic capacity and increase the metabolism of blood lactate within 30 minutes after exercise.