This study evaluated the effect of clinical pathway implemented for Percutaneous Translumeal Coronary Angioplasty ( PTCA ) procedure on patient satisfaction and medical care quality in Taiwan. The study design was the experimental non-equivalent control group type. Secondary data from a large teaching hospital were used, consisting of patient satisfaction survey data of two cohorts of 150 patients each: one cohort treated at the hospital in the year prior to clinical pathway implementation ( experimental group ) and the second cohort, treated in the year after PTCA implementation ( non-equivalent control group ). The 150 patients had been randomly selected out of the total patients treated in each year. The reliability of the questionnaire used for patient satisfaction survey was tested using Cronbach’s alpha statistic. T-test, chi-square tests and multiple regression analysis were done to test the hypotheses that clinical pathway implementation would result in greater patient satisfaction, more efficient care, and fewer undesirable clinical events. The major findings are that (1) After controlling for education, type of caregiver, and past hospitalization experience, clinical pathway implementation was associated with higher patient satisfaction on all five dimensions tested, satisfaction with the discharge process, physician’s care, nursing care, communication with the medical staff, and the care outcomes, (2) Clinical pathwan turn predicted lower length of stay. All five models of patient satisfactioy was associated with better clinical indicators of health care quality, which in showed high R-square values, ranging between 0.30 and 0.57. the greatest increase in satisfaction score was with the communication with clinical staff, which increased by an average of 1.0 point. Estimates of costs per patient, efficiency of care procedures during hospitalization, and avoidance of duplicative clinical investigations all showed a positive impact of clinical pathway implementation. Based on the study findings, it is concluded that clinical pathways have a significant positive impact on quality of care, and patient satisfaction. It is recommended that clinical pathways be implemented for as many procedures as possible.