This case report aimed at describing the nursing experience in caring for a patient with left hemiplegia after stroke. Three major health problems were identified including the feeling of hopelessness, disturbance of physical activity and impaired self-care through observation at interviews, therapeutic relationship, physical examination and Gordon's 11-item functional health pattern assessment guide. Nursing intervention based on Watson's theory in caring was used in this case. After the nursing intervention, the patient overcame these health problems, became more motivated in rehabilitation and improved in the ability of self-care. We hoped this experience might provide other nurses with information about caring for stroke patients in the future.