Objectives: The health promoting hospital (HPH) is a new practice. Organizations must recognize the need to change their service model, plan for health promotion, and educate staff and community about the value of HPHs. The adoption of the HPH is a complicated task that requires great coordination, and an understanding of the crucial factors that influence its development is critical. The aim of this study was to determine the factors that influenced the adoption of the HPH concept by an organization.Methods: Data were collected from the managers HPHs via questionnaire. A total of 134 questionnaires were distributed to 67 hospitals with 83 questionnaires from 41 hospitals returned for a response rate of 61.9%. Data were analyzed using the partial least square technique with Smart PLS software.Results: The complexity of HPHs had a significant negative influence on their adoption. Top management support, a champion, and policy and laws had a significant positive influence on adoption.Conclusions: By identifying the factors that influence the adoption of HPHs, resistance against their development is reduced. With adequate input of resources, an operational mode may be implemented to promote the health of staff, the environment, and connections with the community.