Research is the important process of knowledge exploration. Domain knowledge development can be improved by using research design and proper statistical methods meticulously as well as clearly and systematically displaying research results. In order to find out the evolving trend of Library and Information Science, its research design and statistical method is a topic worth exploring. By applying bibliometric and content analysis, this study investigates the 1,540 research papers published in the Journal of Educational Media & Library Sciences (JoEMLS) in the last 40 years. According to its history and mission statement, the researchers separate time span from 1970 to 2010 into four period, exploring the features of those published papers, including the type of articles, article languages, topics, structures, research designs and statistical methods. The results show as follow. During period 1, the type of articles are diversities. In addition , Chinese papers are dominate. Moreover, the top 3 categories of research papers are the study of “Library and Information Science”(66%), follows by the “Education”(15%). As for the paper structure, there are 2.73% papers applying ILMRAD and only 8 papers of them applying IMRAD. The most commonly adopted research design is Survey Method, among them, the study of “Library and Information Science” used more often (46.63%). As to the most commonly used statistical method is Descriptive Statistics (60.11%), secondly the T-Test(9.27%).