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題名：運動預處理可能減少血漿對離體紅血球脂質氧化作用
書刊名：文化體育學刊
作者：沙部．魯比 引用關係／林嘉志 引用關係／楊忠祥 引用關係
作者(外文)：Sha Pu Lu Bi／Lin, Chia-chih／Yang, Chung-hsiang
出版日期：2013
卷期：16
頁次：頁53-68
主題關鍵詞：氧化傷害；抗氧化酶活性；尿酸；Oxidative damage；Antioxidant enzyme activity；Uric acid
原始連結：連回原系統網址new window
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  • 被引用次數被引用次數:期刊(2) 博士論文(0) 專書(0) 專書論文(0)
  • 排除自我引用排除自我引用:0
  • 共同引用共同引用:8
  • 點閱點閱:157
研究目的：運動預處理已知可減少接續激烈運動引起的氧化傷害，本研究擬探討力竭運動預處理，對紅血球受低氧再充氧處理的影響。方法：研究對象為8位自願參加研究的健康男性（年齡：28.9±8.3 yr，身高：170.1±5.9 cm，體重：68.9±7.4 kg）。採集漸進式運動負荷（graded exercise testing, GXT）跑步前（resting, r）、後（post exercise, e）血液立即離心，分為安靜紅血球（rR）、安靜血漿（rP）、運動紅血球（eR）與運動血漿（eP），並以磷酸緩衝溶液（PBS）重新組合後，比較rWB（r全血）、rRrP（r紅血球 r血漿）、rReP（r紅血球 e血漿）、rRs（r紅血球 磷酸緩衝溶液）。分別處理於低氧（hypobaric hypoxia, PO2=45 mmHg, H）或常氧（normbaric normoxia, PO2=152 mmHg, N）1hr後，再恢復常氧5分鐘（reoxgenation, N）。分析紅血球抗氧化酶活性、脂質氧化傷害指標（TBARS）與上清液尿酸、乳酸與葡萄糖濃度。結果：本研究發現運動預處理後，血漿乳酸（15.26±0.73 mM vs. 2.88±0.19 mM, p
Purpose: Exercise preconditioning has been known to reduce strenuous exercise-induced oxidative damages. To understand the underlining mechanisms, plasma samples isolated from exhausted exercises were used to investigate the possible protection effect on RBC with or without following hypoxia/reoxygenation. Methods: Eight healthy male participants were recruited voluntarily (age: 28.9 ± 8.3 yr, height: 170.1 ± 5.9 cm, weight: 68.9 ± 7.4 kg). Blood samples were collected before (resting, r) and after (post exercise, e) running by Bruce graded exercise testing (GXT). Plasma and RBC were separated and then recombined again into 4 groups: rWB (rWhole Blood), rRrP (rRBC rPlasma), rReP (rRBC ePlasma), rRs (rRBC PBS). All groups were then treated with hypobaric hypoxia at PO2 = 45 mmHg (H/N) or normbaric normoxia at PO2 = 152 mmHg (N/N) for 1 hr and then recovered by N/N for 5 min. Data were to compare differences among the groups at indicators including antioxidant enzyme activities, peroxidized lipid (TBARS), lactate, glucose and uric acid. Results: As compared to the control group, plasma with exercise preconditioning had significantly increased levels of lactate (15.26 ± 0.73 mM vs. 2.88 ± 0.19 mM, p
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學位論文
1.陸康豪(2009)。短時間衝刺對耐力運動後血液氧化壓力的影響(碩士論文)。國立臺灣師範大學。  延伸查詢new window
圖書
1.Kenney, W. L.、Wilmore, J. H.、Costill, D. L.(2011)。Physiology of sport and exercise。Champaign, IL：Human Kinetics Press。  new window
 
 
 
 
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