Ministry of Economic Affairs (MOEA) of Taiwan government decided to construct a low temperature sea water and multipurpose technical R&D model plant in Taitung in 2007. Supported by National Science Council since 2008, professor Lee, C.-L. of Life Science, National Taitung University (NTTU) has found and published in scientific journal that deep sea water (DSW) accelerated the growth of Monascus species and Antrodia camphorota, and the formation of functional metabolites. DSW also accelerated the hypolipidemic effect of Monascus species and liver protection effect of Antrodia camphorota. The Science and Engineering College of NTTU established the DSW R&D Center in May, 2010, Neng-Gao Entertainment Corporation expected the cooperation with NTTU and assisted NTTU establishing the green technology industry master program in Aug, 2011. There were five master degree students graduated with the thesis about thermal energy utilization of DSW, breeding of Agaricus blazei Muril with DSW, coastal recreational activities, attraction of foreign tourists and indigenous peoples’ issues. Four of them had been employed by this company. And there are another five students may graduate in 2014. Since June, 2013, NTTU has cooperated with National Taitung College, and signed the letter of intention with DSW Production Co. Ltd., Neng-Gao Entertainment Corporation, Rich Gate International Ltd., Org. & Nat. Basket Co. Ltd., and Chin- Ang Pharmaceutical Co., Ltd. Supported by Technology Development Program for Academic, MOEA, NTTU has made an effort to the 3-year-research project on key technologies of DSW in Taitung and divided into three parts. A part is accumulating the abilities of research and development, including project office, website, database, patent and technology transfer service, industrial counsel, planning abilities and information exchange platform for industry, government, universities, and research organizations. Besides, president Liu, J.-Y. held a conference and invited domestic and international experts to discuss the water pumping technology. And assistant professor Chen, M.-C. conducted the evaluation of “Cold energy utilization in air conditioning”. B part is bio-functional mechanism, including “Using DSW and its ion develop lactic acid bacteria fermented products that reducing body fat” by associate professor Lee, C.-L., and “Technology of producing natural antioxidan from microalgae cultured by DSW” by assistant professor Twan, W.-H. C part is food utilization including “Manufacturing process study and functional ingredients analysis of DSW plum-wine” by assistant professor Chen, C.-R. and “Research on using DSW in vegetables, meat, and fishery preservation” by associate professor Chang, C.-Y. Promoting Taitung sustainable development is the main duty of NTTU. We plan to develope DSW industry by long-term way, including urging the engagement of more professors and employing new professors, integrating the resources from governments and institutes. We will cooperate with DSW related companies by incubation, researching, education, consultation, shifting patent and technology. We also think that national university offering professional human resources to companies, promoting industry union formation for their image of non-profit and science, strengthening the product credibility is important for the long term development of companies.