This work focuses on the nursing experience encountered while dealing with a hospice patient suffering from pancreatic cancer. From February 7, 2015 to March 1, 2015, patient data were collected by observation and physical assessment, indicating the patient’s major concerns to be pain, powerlessness, and spiritual conflict. Effective management of these concerns involved coordination between the nursing and medical team. In addition to prescribed medications, the patient was also treated music and aromatherapy and kept in a comfortable lying position. During this time, the patient received active care, listening, support, accompaniment skills, and empathy. The collaborative actions of the hospice nurses, social workers and spiritual guidance counselors helped improve the patient’s sense of powerlessness, accept disease status, and resolve the patient’s spiritual conflicts. This case underscores the need for continued promotion of education on how to manage hospice patients. This would further enhance the nurse’s knowledge and skills towards more effective care of patients who are in the terminal stage of life. It is hoped that this brief yet meaningful nursing experience can help highlight some the special nursing problem and encourage further endeavors in the field of hospice care.