This article describes the nursing experience of caring for a 26-year-old female patient at the terminal stage of hepatoma. The patient not only had to adjust to the physiological discomfort but also had to cope with the end of life and separation from her family. The patient was nursed from November 14 to November 30, 2015. Data were collected by observation, interview, and physical assessment. Gordon's 11 Functional Health Patterns were used for evaluation, and the patient was found to have problems of fluid volume excess, body image disturbance, and anticipatory grief. While nursing the patient, the author provided initiative care and continuing nursing care to establish a good relationship with her and her family. Individualized nursing measures were used to solve the patient's physical problems. Low-sodium diets, fluid restriction, and diuretics were applied to improve ascites and edema. Regarding the psychological and spiritual aspects of care, the patient's fear of death, pain of separation from her family, and sorrow regarding her daughter were soothed in the process of making video and audio materials following hospitalization. The author also communicated with family members to overcome a cultural superstition that young people cannot die at home. The patient was then discharged and returned home. For the patient and the family, complete and continuing care was provided. This nursing experience may serve as a reference for people who care for terminally ill patients.