Purposes: The main purpose of the study is to explore how metabolic and physical responses change during Roli ball exercising. The factors we examined were heart rate, relative oxygen uptake, and respiratory rate. Method: Three male students and nine female students from junior college were recruited. Their average age is 16.7±1.0 years, average height is 165.3±8.0 cm, and average weight is 59.8±10.8 kg. After 8 weeks of Roli ball training, subjects were tested for VO2, HR and RR by gradual increase walking for 1.5M, 2.0M, 2.5M and after a 10-minute Roli ball exercising. Results: After Roli ball exercising, the HR (132.7±19.1 /min), VO2 (15.8±3.0 ml/kg/min) and RR(33.4±6.3 /min) of subjects significantly higher than 1.5M gradual increasing walking but lower than 2.0M and 2.5M gradual increasing walking (p<.05). Discussion: Although Roli ball exercise needs highly focused concentration and fine motor skills, physical responses have more significant changes than metabolic responses. Conclusion: The exercise intensity of Roli ball is about 65% of adolescent heart rate, higher than walking but lower than running. Roli ball is more like an aerobic exercise, and it could be included in school aerobics lessons.