Objectives: Population screening to identify children who have developmental delay at an early age is essential to the design of effective intervention programs by child psychiatric services. Early intervention reduces the impact of developmental delay. The Chinese Child Development Inventory (CCDI), a screening tool for developmental delay in children aged below 6 years old, was developed in 1978. However, the validity of the CCDI has not been assessed. The purpose of this study was to assess the validity of the CCDI by using the highly valid BSID as a reference. Methods: In a longitudinal study of a group of 84 Taiwanese children, we evaluated the development simultaneously using CCDI and Bayley Scales of Infant Development (BSID). Results: A poor correlation was found between the two BSID Developmental Indices (DI) and the eight CCDI Development Quotients (DQ), except for one fair correlation between the BSID Psychomotor Index (PDI) and Gross Motor DQ of the CCDI. A high correlation within each one of the eight DQs of CCDI was also found, especially between the General Development Quotient (GDQ) and the other seven DQs. Conclusion: These results suggest that in cases of time or personnel constraints, the General Development Subitem alone may be utilized as a handy screening tool.