To construct an ecologically life & work facilitating urban system in urban agglomerations needs to clarify current situation,spatial heterogeneity and distribution characteristics of the ecological life & work facilitating in urban agglomerations. We can rely on this to promote the ecological life & work facilitating construction of urban agglomerations in a targeted and differential manner. This paper takes the Yangtze River Delta city cluster as an example,constructed the ecological life & work facilitating index system from two aspects including work facilitating and ecological life facilitating,and estimated the ecological life & work facilitating level about 26 cities in 4 provinces of the Yangtze River Delta city cluster from 2005 to 2015. This paper analyzed the spatial heterogeneity and distribution characteristics of ecological life & work facilitating level in the Yangtze River Delta city cluster by using the Moran’s I index and the G index. The main conclusions and policy recommendations cover the following aspects. Firstly,in the past 10 years,the ecological life & work facilitating level of the Yangtze River Delta city cluster has been continuously improved,with high level in the east and low level in the west,the ecological work facilitating level was increasing,but the ecological life facilitating was decreasing. Secondly,in the past 10 years,there was a spatial correlation effect. After 2011,there were significant spatial agglomeration characteristics that‘high-high agglomeration’existed in the east and north,‘low-low agglomeration’in the west and south; it indicated that there was a spatial spillover effect to the development of ecological life & work facilitating level in the Yangtze River Delta city cluster. Thirdly,the spatial distribution of G index tends to agglomerate from the sporadic ‘spot’distribution into‘block’distribution,which showed that the cold spot area and hot spot area of ecological life & work facilitating level were in a trend of strong diffusion effect. Fourthly,while promoting the ecological work facilitating level,we should further promote the ecological life facilitating level. In order to achieve synergistic development of ecological life & work facilitating,the central cities,such as Nanjing,Hangzhou,Hefei,Suzhou,Ningbo and other central cities should play a leading role in the ecological life & work facilitating development of Yangtze River Delta city cluster. Besides,it should utilize the urban ecological resources such as Zhoushan,Xuancheng,Chizhou,Huzhou and Taizhou,and construct a symbiotic urban system for the coordinated development of large,medium and small cities.