This paper reveals the historical and cultural roots of the center-edge dilemma of qualitative research methodology,and the marginalized and aphasic non Anglo and American regional studies under the influence of the dilemma for a long time. The British and American qualitative research methodology and technology have dominated the central position of intellectual production,while non Anglo and American scholars and indigenous studies are labeled as non-modern. In order to break this situation,this paper focuses on the problems of ontological and epistemological basis of British and American qualitative research methodology,and analyzes the precious Chinese philosophic heritage of qualitative research such as the holistic view and the view of change,making an appeal for academic colleagues to be engaged in the discussion of the localization of qualitative research methodology.