Between late 1951 and mid-1952, Mao Zedong launched an anti-corruption campaign which was known as the "Three Anti-" in order to purge the officials of Chinese Communist Party who took bribes or committed embezzlement. The unavoidable result of "Three Anti-" was the persecution of the enterpreneurs and bourgeoisie in China, who finally were exterminated some years later-in 1956. This persecution against the Chinese bourgeoisie in the early 1950s which Mao called it the "Five Anti-" was held in a way of mobilizing the cities dwellers to bring pressure to bear on the victims. In fact, the "Five Anti-" was just a copy of the class struggle in the countryside of China in 1950s. This articles aims at revealing how Mao exerted political manipulation to push the local officials to bring out the "Three Anti-" and "Five Anti-", and what happened to the businessmen and enterpreneurs in the course of the campaigns.