Content analysis of 934 articles published in four major science education journals were conducted. The contents analyzed in this paper were research topics, of research, data collection and data analysis methods, and participants in the studies. The results revealed that the research topics were centered on conceptual learning. The majority of the studies were empirical, focusing mainly on case studies. With respect to the data collection, the single method was used slightly more frequently than the multiple methods, in which tests and questionnaires dominated. Until 2004, there was an increasing tendency for multiple data collection (about 50%) and analysis (about 33%) were shown. In data analysis, the use of a single method exceeds that of the multiple methods, and the quantitative methods involving both t-test and ANOVA are most widely used. The major participants in the studies were students, especially the secondary school students. However, the numbers of the public and others as the subjects were increasing. Finally, it is noted that the four journals analyzed have their own characteristics. The emphasis of the research topics of IJSE and SE was no conceptual learning. In terms of methodology, RISE used less quantitative methods and more descriptive statistics than others.