The article tries to explore the relationship between loan concentration and business performance, NPL of eight domestic public shares of banks which loan to 3D1S industries. In empirical study, we firstly obtained the loan concentration of eight banks to the 3D1S industries, then apply the panel regression model to discuss the relationship between loan concentration and business performance, NPL, respectively. The empirical results show that loan concentration of 3D1S industry has a positive significant effect on the bank's business performance and the NPL ratio. This means that the loan concentration does help to improve return of asset (ROA) and return of equity (ROE). However, the loan concentrated in certain industries will result a high credit risk concentration and relatively high NPL ratio. The allowances for bad debts and business performance show a significant positive relationship. It implies that the better quality of bank assets, the better business performance. The loan-to-deposit Ratio and NPL ratio presents a significant positive relationship, which means that higher loan-to-deposit ratio, the chance of occurrence of non-performing loans may be greater. Whereas the scale of asset and return of equity (ROE), NPL also shows a significant positive relationship, which implies that when the scale of bank is larger, will has a relatively high amount of loan and interest income, respectively. It will cause a relatively higher chance of bad debt.