本研究目的在探討短期間攝取槲皮素對單次激烈運動之運動表現及運動後恢復期生理疲勞與心理反應之影響。以12位健康男大學生為研究對象，採雙盲交叉測驗設計，隨機分配補充一：槲皮素（Quercetin，QE）2 × 500 mg／天，或二、安慰劑（Placebo，PL），連續7天後，進行單次激烈運動（75% VO2max）至力竭，分析最大攝氧量及運動至力竭時間，並於運動前與恢復期0、10、20、30及60分鐘測驗心跳率、血壓及記錄心理情緒狀態評估量表。血乳酸於運動前與恢復期0、30及60分鐘測定；測驗完畢後隔7天飲食排空期，再進行補充劑之交換。研究結果顯示：QE組最大攝氧量顯著高於PL組；QE組運動至力竭時間較PL組延長11%，但未達顯著差異；於運動恢復期60分鐘，QE組之乳酸值顯著低於PL組，且QE組於激烈運動後收縮壓也顯著低於PL組，而在運動後恢復期20分鐘，QE組心跳的恢復能力顯著大於PL組；此外，QE組在運動休息後POMS的疲勞分數及負面情緒因子皆顯著低於PL組。本研究結論：攝取槲皮素可促進最大攝氧量並有助於減輕激烈運動後恢復期的生理性疲勞和負面情緒的改善。

The purpose of this study was to investigate the effects of short-term quercetin (QE) intake on exercise performance, physiological fatigue and emotional responses during the recovery after a single bout of high intensity exercise. Twelve healthy male college students were double blindly and randomly assigned into quercetin (QE) intake trial (2 × 500 mg/day) or placebo-controlled trial (PL). The treatment was given for 7 continuous days, and then subjects performed a single bout of intensive exercise (75% VO2max) until exhaustion. Exercise duration to exhaust and VO2max were recorded before exercise. Other tests, such as heart rate, blood pressure, and profile of mood states (POMS) were conducted and analyzed before exercise and during recovery at 0, 10, 20, 30, and 60 minutes after exercise. However, the changes in lactate concentrations were tested only before exercise, and 0, 30 and 60 minutes after exercise. After completion of the trial, subjects were cross-over and the same protocols were repeated with one-week interval. The results revealed that subjects in QE trial had significantly higher VO2max compared to PL trial. Exercise time to exhaust in QE trial was longer than PE by 11%, but no significant difference. Furthermore, lactate concentration in QE trial was significantly lower than PL trial during 60 minute recovery period. The systolic blood pressure in QE trial was also lower than PL trial. However, QE trial recovered quicker in the change of heart rate than PL trial at 20 minute recovery period. In addition, the scores of fatigue and negative mental factors in POMS for QE trial were also significantly lower than PL trial. This study concluded that QE may enhance the performance of VO2max, delay physical fatigue, and improve negative emotion after an intensive exercise.